1 HAMP#1
116-183 aa · 68 aa · 16.6% of protein
Raw token
HAMP:116:0.0000000000047:183:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE78_RS17695
Histidine kinase, Classic
Clostridioides difficile · GCF_021283745
ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021283745#LWE78_RS17695Stable P2CS identifier used across views.
GenomeGCF_021283745Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 410 aa (52.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa410 aa
Domain-by-domain annotation3 items
2 HisKA#2
195-254 aa · 60 aa · 14.6% of protein
Raw token
HisKA:195:0.000000000205:254:61:643 HATPase_c#3
301-385 aa · 85 aa · 20.7% of protein
Raw token
HATPase_c:301:0.00000000000000108:385:88:109- Raw architecture: HAMP:116:0.0000000000047:183:68:69#HisKA:195:0.000000000205:254:61:64#HATPase_c:301:0.00000000000000108:385:88:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_021283745::NZ_JAJSOB010000316.1::G00042
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1235Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE78_17695RefSeq proteinWP_131042143.1
Context group ID
GCF_021283745::NZ_JAJSOB010000316.1::G00042Context members
LWE78_RS17695
Partner locus tags
LWE78_RS17695
Partner old locus tags
LWE78_17695
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131042143.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE78_RS17695Primary locus identifier stored in the genes table.
Old locus tagLWE78_17695Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSOB010000316.1Sequence record reported by the local genomic context database.
Genomic interval1-1 235 nt1 235 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 235 ntGCF_021283745::NZ_JAJSOB010000316.1::G00042
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021283745::NZ_JAJSOB010000316.1::G00042Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSOB010000316.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 235 nt1 235 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 235 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
LWE78_RS17695GCF_021283745#LWE78_RS17695
HKClassicCurrent focus
1-1 235 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0202465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1783726
Simplified PFAM architecture for HKOC_1783726
PFAM domain coverage: 195 / 464 aa (42.0%)
1 aa464 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[187-236] | HisKA[250-308] | HATPase_c[355-440]
- Domain count: 3
- Matched identifier: HKOC_1783726
- Positioned domains: HAMP 187-236 ; HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0202465
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283745
AssemblyASM2128374v1 · Contighaploid
Genome composition3 912 665 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key