Gene detail

LWE71_RS17115

Histidine kinase, Classic

Clostridioides difficile · GCF_021283685

ClassHKTypeClassicLength404 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021283685#LWE71_RS17115Stable P2CS identifier used across views.
GenomeGCF_021283685Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1783726Run 6 · 289 sequences · id 100% · cov 80%
External referencesWP_232922752.1 · MIST4 LWE71_RS17115RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length404 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 404 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for LWE71_RS17115
Domain-by-domain annotation3 items
1 HAMP#1
110-177 aa · 68 aa · 16.8% of protein
Raw tokenHAMP:110:0.00000000000473:177:68:69
2 HisKA#2
189-248 aa · 60 aa · 14.9% of protein
Raw tokenHisKA:189:0.000000000196:248:61:64
3 HATPase_c#3
295-379 aa · 85 aa · 21.0% of protein
Raw tokenHATPase_c:295:0.00000000000000107:379:88:109
  • Raw architecture: HAMP:110:0.00000000000473:177:68:69#HisKA:189:0.000000000196:248:61:64#HATPase_c:295:0.00000000000000107:379:88:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_021283685::NZ_JAJSMQ010000696.1::G00038
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1216Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE71_17150RefSeq proteinWP_232922752.1
Context group IDGCF_021283685::NZ_JAJSMQ010000696.1::G00038
Context members
LWE71_RS17115
Partner locus tags
LWE71_RS17115
Partner old locus tags
LWE71_17150
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_232922752.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE71_RS17115Primary locus identifier stored in the genes table.
Old locus tagLWE71_17150Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMQ010000696.1Sequence record reported by the local genomic context database.
Genomic interval1-1 216 nt1 216 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 216 ntGCF_021283685::NZ_JAJSMQ010000696.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021283685::NZ_JAJSMQ010000696.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMQ010000696.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 216 nt1 216 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 216 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1783726Run 6 · HK · 289 sequences
Representative sequenceGCF_000155065#QAE_RS0202465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1783726

Simplified PFAM architecture for HKOC_1783726

PFAM domain coverage: 195 / 464 aa (42.0%)

1 aa464 aa
HAMP: 187-236 aaHAMPHisKA: 250-308 aaHisKAHATPase_c: 355-440 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[187-236] | HisKA[250-308] | HATPase_c[355-440]
  • Domain count: 3
  • Matched identifier: HKOC_1783726
  • Positioned domains: HAMP 187-236 ; HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0202465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283685
AssemblyASM2128368v1 · Contighaploid
Genome composition3 837 771 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 46 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key