Gene detail

LWE71_RS16535

Histidine kinase, Classic

Clostridioides difficile · GCF_021283685

ClassHKTypeClassicLength316 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283685#LWE71_RS16535Stable P2CS identifier used across views.
GenomeGCF_021283685Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550121Run 6 · 307 sequences · id 100% · cov 80%
External referencesWP_232922736.1 · MIST4 LWE71_RS16535RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length316 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 316 aa (47.8%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa316 aa
HisKA_3: 117-182 aa (66 aa)1HATPase_c: 223-307 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
117-182 aa · 66 aa · 20.9% of protein
Raw tokenHisKA_3:117:2.63e-21:182:67:68
2 HATPase_c#2
223-307 aa · 85 aa · 26.9% of protein
Raw tokenHATPase_c:223:0.000000000772:307:104:109
  • Raw architecture: HisKA_3:117:2.63e-21:182:67:68#HATPase_c:223:0.000000000772:307:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021283685::NZ_JAJSMQ010000624.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span51-1643Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE71_16560RefSeq proteinWP_232922736.1
Context group IDGCF_021283685::NZ_JAJSMQ010000624.1::G00027
Context members
LWE71_RS16530LWE71_RS16535
Partner locus tags
LWE71_RS16530LWE71_RS16535
Partner old locus tags
LWE71_16555LWE71_16560
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_232922736.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE71_RS16535Primary locus identifier stored in the genes table.
Old locus tagLWE71_16560Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMQ010000624.1Sequence record reported by the local genomic context database.
Genomic interval691-1 643 nt953 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span51-1 643 ntGCF_021283685::NZ_JAJSMQ010000624.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021283685::NZ_JAJSMQ010000624.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMQ010000624.1All displayed genes belong to this local TCS context.
Neighborhood span51-1 643 nt1 593 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
51 nt1 643 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE71_RS16530GCF_021283685#LWE71_RS16530
RRNarL

51-698 nt · Reverse (-)

Old locus LWE71_16555RefSeq WP_009905386.1
LWE71_RS16535GCF_021283685#LWE71_RS16535
HKClassicCurrent focus

691-1 643 nt · Reverse (-)

Old locus LWE71_16560RefSeq WP_232922736.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550121Run 6 · HK · 307 sequences
Representative sequenceGCF_000155065#QAE_RS0206215Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550121

Simplified PFAM architecture for HKOC_2550121

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550121
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0206215

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283685
AssemblyASM2128368v1 · Contighaploid
Genome composition3 837 771 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 46 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key