1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw token
HisKA:185:0.000000000193:250:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE71_RS08640
Histidine kinase, Classic
Clostridioides difficile · GCF_021283685
ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283685#LWE71_RS08640Stable P2CS identifier used across views.
GenomeGCF_021283685Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa410 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw token
HATPase_c:296:4.88e-25:408:113:109- Raw architecture: HisKA:185:0.000000000193:250:66:64#HATPase_c:296:4.88e-25:408:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_021283685::NZ_JAJSMQ010000165.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4892-6785Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE71_08665RefSeq proteinWP_003420373.1
Context group ID
GCF_021283685::NZ_JAJSMQ010000165.1::G00004Context members
LWE71_RS08635LWE71_RS08640
Partner locus tags
LWE71_RS08635LWE71_RS08640
Partner old locus tags
LWE71_08660LWE71_08665
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003420373.1Primary protein accession used for annex mappings.
UniProt accessionD5Q708Primary UniProt accession resolved in the annex database.
UniProt IDD5Q708_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE71_RS08640Primary locus identifier stored in the genes table.
Old locus tagLWE71_08665Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMQ010000165.1Sequence record reported by the local genomic context database.
Genomic interval5 553-6 785 nt1 233 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 892-6 785 ntGCF_021283685::NZ_JAJSMQ010000165.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021283685::NZ_JAJSMQ010000165.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMQ010000165.1All displayed genes belong to this local TCS context.
Neighborhood span4 892-6 785 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 892 nt6 785 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWE71_RS08635GCF_021283685#LWE71_RS08635
RROmpR
4 892-5 563 nt · Forward (+)
LWE71_RS08640GCF_021283685#LWE71_RS08640
HKClassicCurrent focus
5 553-6 785 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0208365Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2354207
Simplified PFAM architecture for HKOC_2354207
PFAM domain coverage: 178 / 410 aa (43.4%)
1 aa410 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[185-250] | HATPase_c[297-408]
- Domain count: 2
- Matched identifier: HKOC_2354207
- Positioned domains: HisKA 185-250 ; HATPase_c 297-408
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0208365
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283685
AssemblyASM2128368v1 · Contighaploid
Genome composition3 837 771 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 46 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key