Gene detail

LWF03_RS09485

Histidine kinase, Classic

Clostridioides difficile · GCF_021283665

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283665#LWF03_RS09485Stable P2CS identifier used across views.
GenomeGCF_021283665Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503304Run 6 · 294 sequences · id 100% · cov 80%
External referencesWP_003422313.1 · D5Q9X2 · MIST4 LWF03_RS09485RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for LWF03_RS09485
Domain-by-domain annotation2 items
1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw tokenHisKA:168:0.000000000000401:234:67:64
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw tokenHATPase_c:280:4.98e-26:388:110:109
  • Raw architecture: HisKA:168:0.000000000000401:234:67:64#HATPase_c:280:4.98e-26:388:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021283665::NZ_JAJSOE010000078.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1819-3682Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWF03_09485RefSeq proteinWP_003422313.1
Context group IDGCF_021283665::NZ_JAJSOE010000078.1::G00026
Context members
LWF03_RS09480LWF03_RS09485
Partner locus tags
LWF03_RS09480LWF03_RS09485
Partner old locus tags
LWF03_09480LWF03_09485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003422313.1Primary protein accession used for annex mappings.
UniProt accessionD5Q9X2Primary UniProt accession resolved in the annex database.
UniProt IDD5Q9X2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWF03_RS09485Primary locus identifier stored in the genes table.
Old locus tagLWF03_09485Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSOE010000078.1Sequence record reported by the local genomic context database.
Genomic interval2 501-3 682 nt1 182 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 819-3 682 ntGCF_021283665::NZ_JAJSOE010000078.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021283665::NZ_JAJSOE010000078.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSOE010000078.1All displayed genes belong to this local TCS context.
Neighborhood span1 819-3 682 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 819 nt3 682 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWF03_RS09480GCF_021283665#LWF03_RS09480
RROmpR

1 819-2 511 nt · Forward (+)

Old locus LWF03_09480RefSeq WP_003422314.1
LWF03_RS09485GCF_021283665#LWF03_RS09485
HKClassicCurrent focus

2 501-3 682 nt · Forward (+)

Old locus LWF03_09485RefSeq WP_003422313.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503304Run 6 · HK · 294 sequences
Representative sequenceGCF_000155065#QAE_RS0217715Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503304

Simplified PFAM architecture for HKOC_2503304

PFAM domain coverage: 175 / 393 aa (44.5%)

1 aa393 aa
HisKA: 168-233 aaHisKAHATPase_c: 281-389 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[168-233] | HATPase_c[281-389]
  • Domain count: 2
  • Matched identifier: HKOC_2503304
  • Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0217715

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283665
AssemblyASM2128366v1 · Contighaploid
Genome composition3 907 427 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 47 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key