Gene detail

LWE91_RS14150

Histidine kinase, Classic

Clostridioides difficile · GCF_021283625

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_021283625#LWE91_RS14150Stable P2CS identifier used across views.
GenomeGCF_021283625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842458Run 6 · 299 sequences · id 100% · cov 80%
External referencesWP_009906364.1 · MIST4 LWE91_RS14150RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
HisKA: 449-514 aa (66 aa)1HATPase_c: 565-668 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000819:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:4.65e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000819:514:66:64#HATPase_c:565:4.65e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_021283625::NZ_JAJSNB010000241.1::G00005
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span531-4025Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE91_14150RefSeq proteinWP_009906364.1
Context group IDGCF_021283625::NZ_JAJSNB010000241.1::G00005
Context members
LWE91_RS14145LWE91_RS14150LWE91_RS14155
Partner locus tags
LWE91_RS14145LWE91_RS14150LWE91_RS14155
Partner old locus tags
LWE91_14145LWE91_14150LWE91_14155

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009906364.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE91_RS14150Primary locus identifier stored in the genes table.
Old locus tagLWE91_14150Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNB010000241.1Sequence record reported by the local genomic context database.
Genomic interval1 280-3 295 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span531-4 025 ntGCF_021283625::NZ_JAJSNB010000241.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021283625::NZ_JAJSNB010000241.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNB010000241.1All displayed genes belong to this local TCS context.
Neighborhood span531-4 025 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
531 nt4 025 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

LWE91_RS14145GCF_021283625#LWE91_RS14145
RROmpR

531-1 208 nt · Forward (+)

Old locus LWE91_14145RefSeq WP_003417201.1
LWE91_RS14150GCF_021283625#LWE91_RS14150
HKClassicCurrent focus

1 280-3 295 nt · Forward (+)

Old locus LWE91_14150RefSeq WP_009906364.1
LWE91_RS14155GCF_021283625#LWE91_RS14155
RROmpR

3 345-4 025 nt · Forward (+)

Old locus LWE91_14155RefSeq WP_003417207.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842458Run 6 · HK · 299 sequences
Representative sequenceGCF_000155065#QAE_RS0216030Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842458

Simplified PFAM architecture for HKOC_0842458

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842458
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0216030

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283625
AssemblyASM2128362v1 · Contighaploid
Genome composition3 919 288 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 46 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key