Gene detail

LK487_RS01100

Histidine kinase, CheA

Agathobacter rectalis · GCF_020708695

ClassHKTypeCheALength706 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_020708695#LK487_RS01100Stable P2CS identifier used across views.
GenomeGCF_020708695Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter
Selected clusterHKOC_0757396Run 6 · 26 sequences · id 100% · cov 80%
External referencesWP_012742625.1 · C4ZA86 · MIST4 LK487_RS01100RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length706 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage426 / 706 aa (60.3%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa706 aa
Hpt: 5-98 aa (94 aa)1H-kinase_dim: 324-387 aa (64 aa)2HATPase_c: 435-574 aa (140 aa)3CheW: 579-706 aa (128 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
5-98 aa · 94 aa · 13.3% of protein
Raw tokenHpt:5:2.17e-17:98:94:84
2 H-kinase_dim#2
324-387 aa · 64 aa · 9.1% of protein
Raw tokenH-kinase_dim:324:0.00000000000000122:387:67:67
3 HATPase_c#3
435-574 aa · 140 aa · 19.8% of protein
Raw tokenHATPase_c:435:3.84e-16:574:140:109
4 CheW#4
579-706 aa · 128 aa · 18.1% of protein
Raw tokenCheW:579:2.49e-30:706:135:138
  • Raw architecture: Hpt:5:2.17e-17:98:94:84#H-kinase_dim:324:0.00000000000000122:387:67:67#HATPase_c:435:3.84e-16:574:140:109#CheW:579:2.49e-30:706:135:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_020708695::NZ_JAJFBX010000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span230401-233584Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLK487_01100RefSeq proteinWP_012742625.1
Context group IDGCF_020708695::NZ_JAJFBX010000001.1::G00002
Context members
LK487_RS01100LK487_RS01105
Partner locus tags
LK487_RS01100LK487_RS01105
Partner old locus tags
LK487_01100LK487_01105
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012742625.1Primary protein accession used for annex mappings.
UniProt accessionC4ZA86Primary UniProt accession resolved in the annex database.
UniProt IDC4ZA86_AGARVDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLK487_RS01100Primary locus identifier stored in the genes table.
Old locus tagLK487_01100Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJFBX010000001.1Sequence record reported by the local genomic context database.
Genomic interval230 401-232 521 nt2 121 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span230 401-233 584 ntGCF_020708695::NZ_JAJFBX010000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_020708695::NZ_JAJFBX010000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJFBX010000001.1All displayed genes belong to this local TCS context.
Neighborhood span230 401-233 584 nt3 184 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
230 401 nt233 584 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LK487_RS01100GCF_020708695#LK487_RS01100
HKCheACurrent focus

230 401-232 521 nt · Reverse (-)

Old locus LK487_01100RefSeq WP_012742625.1
LK487_RS01105GCF_020708695#LK487_RS01105
RRCheB

232 523-233 584 nt · Reverse (-)

Old locus LK487_01105RefSeq WP_012742626.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0757396Run 6 · HK · 26 sequences
Representative sequenceGCF_000020605#EUBREC_RS08005Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0757396

Simplified PFAM architecture for HKOC_0757396

PFAM domain coverage: 502 / 706 aa (71.1%)

1 aa706 aa
Hpt: 5-97 aaHptP2: 183-260 aaP2H-kinase_dim: 323-387 aaH-kinase_dimHATPase_c: 436-574 aaHATPase_cCheW: 579-705 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[5-97] | P2[183-260] | H-kinase_dim[323-387] | HATPase_c[436-574] | CheW[579-705]
  • Domain count: 5
  • Matched identifier: HKOC_0757396
  • Positioned domains: Hpt 5-97 ; P2 183-260 ; H-kinase_dim 323-387 ; HATPase_c 436-574 ; CheW 579-705
Cluster members and taxonomy
Visualization

Representative gene: GCF_000020605#EUBREC_RS08005

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 491 · GCF_020708695
AssemblyASM2070869v1 · Contighaploid
Genome composition3 717 369 bp · 41,5% GCAgathobacter rectalis
Signal transduction countsGenes 88 · HK 35 · RR 50CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAgathobacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Agathobacter

Related genes

Preview from the same derived genome key