1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw token
HisKA:117:0.000000000161:177:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HO256_RS17610
Histidine kinase, Classic
Clostridioides difficile · GCF_020295225
ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_020295225#HO256_RS17610Stable P2CS identifier used across views.
GenomeGCF_020295225Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa329 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw token
HATPase_c:222:6.69e-24:328:107:109- Raw architecture: HisKA:117:0.000000000161:177:61:64#HATPase_c:222:6.69e-24:328:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_020295225::NZ_JABGDJ010000017.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span814-2476Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHO256_17530RefSeq proteinWP_003434897.1
Context group ID
GCF_020295225::NZ_JABGDJ010000017.1::G00009Context members
HO256_RS17605HO256_RS17610
Partner locus tags
HO256_RS17605HO256_RS17610
Partner old locus tags
HO256_17525HO256_17530
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003434897.1Primary protein accession used for annex mappings.
UniProt accessionQ181I8Primary UniProt accession resolved in the annex database.
UniProt IDQ181I8_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHO256_RS17610Primary locus identifier stored in the genes table.
Old locus tagHO256_17530Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JABGDJ010000017.1Sequence record reported by the local genomic context database.
Genomic interval1 487-2 476 nt990 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span814-2 476 ntGCF_020295225::NZ_JABGDJ010000017.1::G00009
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_020295225::NZ_JABGDJ010000017.1::G00009Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JABGDJ010000017.1All displayed genes belong to this local TCS context.
Neighborhood span814-2 476 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
814 nt2 476 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HO256_RS17605GCF_020295225#HO256_RS17605
RROmpR
814-1 500 nt · Forward (+)
HO256_RS17610GCF_020295225#HO256_RS17610
HKClassicCurrent focus
1 487-2 476 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS19070Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2857938
Simplified PFAM architecture for HKOC_2857938
PFAM domain coverage: 169 / 329 aa (51.4%)
1 aa329 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[116-177] | HATPase_c[222-328]
- Domain count: 2
- Matched identifier: HKOC_2857938
- Positioned domains: HisKA 116-177 ; HATPase_c 222-328
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS19070
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_020295225
AssemblyASM2029522v1 · Scaffoldhaploid
Genome composition4 064 627 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 46 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key