Gene detail

HO258_RS00985

Histidine kinase, Classic

Clostridioides difficile · GCF_020295205

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_020295205#HO258_RS00985Stable P2CS identifier used across views.
GenomeGCF_020295205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842418Run 6 · 344 sequences · id 100% · cov 80%
External referencesWP_009893921.1 · A0A0H3NB90 · MIST4 HO258_RS00985RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
HisKA: 449-514 aa (66 aa)1HATPase_c: 565-668 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000911:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:2.91e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000911:514:66:64#HATPase_c:565:2.91e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_020295205::NZ_JABGDK010000001.1::G00023
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span227303-233028Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHO258_00990RefSeq proteinWP_009893921.1
Context group IDGCF_020295205::NZ_JABGDK010000001.1::G00023
Context members
HO258_RS00970HO258_RS00975HO258_RS00980HO258_RS00985HO258_RS00990
Partner locus tags
HO258_RS00970HO258_RS00975HO258_RS00980HO258_RS00985HO258_RS00990
Partner old locus tags
HO258_00975HO258_00980HO258_00985HO258_00990HO258_00995

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893921.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NB90Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NB90_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHO258_RS00985Primary locus identifier stored in the genes table.
Old locus tagHO258_00990Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JABGDK010000001.1Sequence record reported by the local genomic context database.
Genomic interval230 264-232 279 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span227 303-233 028 ntGCF_020295205::NZ_JABGDK010000001.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_020295205::NZ_JABGDK010000001.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JABGDK010000001.1All displayed genes belong to this local TCS context.
Neighborhood span227 303-233 028 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
227 303 nt233 028 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

HO258_RS00970GCF_020295205#HO258_RS00970
HKClassic

227 303-228 418 nt · Reverse (-)

Old locus HO258_00975RefSeq WP_009891726.1
HO258_RS00975GCF_020295205#HO258_RS00975
RROmpR

228 454-229 152 nt · Reverse (-)

Old locus HO258_00980RefSeq WP_009891729.1
HO258_RS00980GCF_020295205#HO258_RS00980
RROmpR

229 534-230 214 nt · Reverse (-)

Old locus HO258_00985RefSeq WP_009891737.1
HO258_RS00985GCF_020295205#HO258_RS00985
HKClassicCurrent focus

230 264-232 279 nt · Reverse (-)

Old locus HO258_00990RefSeq WP_009893921.1
HO258_RS00990GCF_020295205#HO258_RS00990
RROmpR

232 351-233 028 nt · Reverse (-)

Old locus HO258_00995RefSeq WP_009891739.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842418Run 6 · HK · 344 sequences
Representative sequenceGCF_000003215#QAC_RS0216530Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842418

Simplified PFAM architecture for HKOC_0842418

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842418
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0216530

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_020295205
AssemblyASM2029520v1 · Scaffoldhaploid
Genome composition4 114 262 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 108 · HK 51 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key