Gene detail

HL558_RS00775

Histidine kinase, Classic

Clostridioides difficile · GCF_020295125

ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_020295125#HL558_RS00775Stable P2CS identifier used across views.
GenomeGCF_020295125Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0599072Run 6 · 39 sequences · id 100% · cov 80%
External referencesWP_225541028.1 · MIST4 HL558_RS00775RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HL558_RS00775
Domain-by-domain annotation2 items
1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw tokenHisKA:558:1.65e-18:624:67:64
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw tokenHATPase_c:671:0.000000000398:775:110:109
  • Raw architecture: HisKA:558:1.65e-18:624:67:64#HATPase_c:671:0.000000000398:775:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_020295125::NZ_JABGDG010000001.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span177609-180633Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHL558_00775RefSeq proteinWP_225541028.1
Context group IDGCF_020295125::NZ_JABGDG010000001.1::G00009
Context members
HL558_RS00770HL558_RS00775
Partner locus tags
HL558_RS00770HL558_RS00775
Partner old locus tags
HL558_00770HL558_00775
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_225541028.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHL558_RS00775Primary locus identifier stored in the genes table.
Old locus tagHL558_00775Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JABGDG010000001.1Sequence record reported by the local genomic context database.
Genomic interval178 297-180 633 nt2 337 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span177 609-180 633 ntGCF_020295125::NZ_JABGDG010000001.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_020295125::NZ_JABGDG010000001.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JABGDG010000001.1All displayed genes belong to this local TCS context.
Neighborhood span177 609-180 633 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
177 609 nt180 633 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HL558_RS00770GCF_020295125#HL558_RS00770
RROmpR

177 609-178 325 nt · Forward (+)

Old locus HL558_00770RefSeq WP_003431132.1
HL558_RS00775GCF_020295125#HL558_RS00775
HKClassicCurrent focus

178 297-180 633 nt · Forward (+)

Old locus HL558_00775RefSeq WP_225541028.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0599072Run 6 · HK · 39 sequences
Representative sequenceGCF_000448905#QAY_RS12650Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0599072

Simplified PFAM architecture for HKOC_0599072

PFAM domain coverage: 172 / 778 aa (22.1%)

1 aa778 aa
HisKA: 558-624 aaHisKAHATPase_c: 671-775 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[558-624] | HATPase_c[671-775]
  • Domain count: 2
  • Matched identifier: HKOC_0599072
  • Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448905#QAY_RS12650

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_020295125
AssemblyASM2029512v1 · Scaffoldhaploid
Genome composition4 205 428 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key