Gene detail

K8P06_RS13610

Histidine kinase, Classic

Clostridioides difficile · GCF_019931025

ClassHKTypeClassicLength435 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_019931025#K8P06_RS13610Stable P2CS identifier used across views.
GenomeGCF_019931025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2122086Run 6 · 204 sequences · id 100% · cov 80%
External referencesWP_330360718.1 · MIST4 K8P06_RS13610RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length435 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 435 aa (56.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa435 aa
HAMP: 127-200 aa (74 aa)1HisKA: 211-276 aa (66 aa)2HATPase_c: 326-432 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
127-200 aa · 74 aa · 17.0% of protein
Raw tokenHAMP:127:0.00000000417:200:74:69
2 HisKA#2
211-276 aa · 66 aa · 15.2% of protein
Raw tokenHisKA:211:0.00000000351:276:66:64
3 HATPase_c#3
326-432 aa · 107 aa · 24.6% of protein
Raw tokenHATPase_c:326:1.85e-25:432:107:109
  • Raw architecture: HAMP:127:0.00000000417:200:74:69#HisKA:211:0.00000000351:276:66:64#HATPase_c:326:1.85e-25:432:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_019931025::NZ_CP082868.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2858527-2860662Genomic interval covered by the local TCS group.
Identifiers
Old locus tagK8P06_13480RefSeq proteinWP_330360718.1
Context group IDGCF_019931025::NZ_CP082868.1::G00039
Context members
K8P06_RS13605K8P06_RS13610
Partner locus tags
K8P06_RS13605K8P06_RS13610
Partner old locus tags
K8P06_13475K8P06_13480
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330360718.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagK8P06_RS13610Primary locus identifier stored in the genes table.
Old locus tagK8P06_13480Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP082868.1Sequence record reported by the local genomic context database.
Genomic interval2 859 355-2 860 662 nt1 308 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 858 527-2 860 662 ntGCF_019931025::NZ_CP082868.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_019931025::NZ_CP082868.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP082868.1All displayed genes belong to this local TCS context.
Neighborhood span2 858 527-2 860 662 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 858 527 nt2 860 662 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

K8P06_RS13605GCF_019931025#K8P06_RS13605
RROmpR

2 858 527-2 859 219 nt · Forward (+)

Old locus K8P06_13475RefSeq WP_003417590.1
K8P06_RS13610GCF_019931025#K8P06_RS13610
HKClassicCurrent focus

2 859 355-2 860 662 nt · Forward (+)

Old locus K8P06_13480RefSeq WP_330360718.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2122086Run 6 · HK · 204 sequences
Representative sequenceGCF_000164655#HMPREF0219_RS16665Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2122086

Simplified PFAM architecture for HKOC_2122086

PFAM domain coverage: 222 / 435 aa (51.0%)

1 aa435 aa
HAMP: 150-199 aaHAMPHisKA: 212-276 aaHisKAHATPase_c: 326-432 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[150-199] | HisKA[212-276] | HATPase_c[326-432]
  • Domain count: 3
  • Matched identifier: HKOC_2122086
  • Positioned domains: HAMP 150-199 ; HisKA 212-276 ; HATPase_c 326-432
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164655#HMPREF0219_RS16665

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_019931025
AssemblyASM1993102v1 · Complete Genomehaploid
Genome composition4 045 616 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key