Gene detail

HCG72_RS06645

Histidine kinase, Classic

Bifidobacterium longum · GCF_019734255

ClassHKTypeClassicLength565 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_019734255#HCG72_RS06645Stable P2CS identifier used across views.
GenomeGCF_019734255Bacteria; Bacillati; Actinomycetota; Actinomycetes; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium
Selected clusterHKOC_1234005Run 6 · 44 sequences · id 100% · cov 80%
External referencesWP_010081555.1 · A0A0S2ML06 · MIST4 HCG72_RS06645RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length565 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 565 aa (43.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa565 aa
HAMP: 209-278 aa (70 aa)1HisKA: 290-356 aa (67 aa)2HATPase_c: 403-513 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
209-278 aa · 70 aa · 12.4% of protein
Raw tokenHAMP:209:1.46e-16:278:70:69
2 HisKA#2
290-356 aa · 67 aa · 11.9% of protein
Raw tokenHisKA:290:0.0000000000000641:356:67:64
3 HATPase_c#3
403-513 aa · 111 aa · 19.6% of protein
Raw tokenHATPase_c:403:6.91e-30:513:111:109
  • Raw architecture: HAMP:209:1.46e-16:278:70:69#HisKA:290:0.0000000000000641:356:67:64#HATPase_c:403:6.91e-30:513:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_019734255::NZ_JAASHH010000007.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span54493-56909Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHCG72_06700RefSeq proteinWP_010081555.1
Context group IDGCF_019734255::NZ_JAASHH010000007.1::G00012
Context members
HCG72_RS06645HCG72_RS06650
Partner locus tags
HCG72_RS06645HCG72_RS06650
Partner old locus tags
HCG72_06700HCG72_06705
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_010081555.1Primary protein accession used for annex mappings.
UniProt accessionA0A0S2ML06Primary UniProt accession resolved in the annex database.
UniProt IDA0A0S2ML06_BIFLLDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHCG72_RS06645Primary locus identifier stored in the genes table.
Old locus tagHCG72_06700Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAASHH010000007.1Sequence record reported by the local genomic context database.
Genomic interval54 493-56 190 nt1 698 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span54 493-56 909 ntGCF_019734255::NZ_JAASHH010000007.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_019734255::NZ_JAASHH010000007.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAASHH010000007.1All displayed genes belong to this local TCS context.
Neighborhood span54 493-56 909 nt2 417 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
54 493 nt56 909 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HCG72_RS06645GCF_019734255#HCG72_RS06645
HKClassicCurrent focus

54 493-56 190 nt · Reverse (-)

Old locus HCG72_06700RefSeq WP_010081555.1
HCG72_RS06650GCF_019734255#HCG72_RS06650
RROmpR

56 187-56 909 nt · Reverse (-)

Old locus HCG72_06705RefSeq WP_011067923.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1234005Run 6 · HK · 44 sequences
Representative sequenceGCF_000008945#BLD_RS00280Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1234005

Simplified PFAM architecture for HKOC_1234005

PFAM domain coverage: 230 / 565 aa (40.7%)

1 aa565 aa
HAMP: 226-278 aaHAMPHisKA: 290-356 aaHisKAHATPase_c: 403-512 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[226-278] | HisKA[290-356] | HATPase_c[403-512]
  • Domain count: 3
  • Matched identifier: HKOC_1234005
  • Positioned domains: HAMP 226-278 ; HisKA 290-356 ; HATPase_c 403-512
Cluster members and taxonomy
Visualization

Representative gene: GCF_000008945#BLD_RS00280

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 216 816 · GCF_019734255
AssemblyASM1973425v1 · Scaffoldhaploid
Genome composition2 349 044 bp · 60,0% GCBifidobacterium longum
Signal transduction countsGenes 24 · HK 10 · RR 12CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumActinomycetotaClassActinomycetesOrderBifidobacterialesFamilyBifidobacteriaceaeGenusBifidobacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Actinomycetota4Actinomycetes5Bifidobacteriales6Bifidobacteriaceae7Bifidobacterium

Related genes

Preview from the same derived genome key