Gene detail

K1N48_RS12695

Histidine kinase, Classic

Clostridioides difficile · GCF_019427665

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_019427665#K1N48_RS12695Stable P2CS identifier used across views.
GenomeGCF_019427665Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1737648Run 6 · 296 sequences · id 100% · cov 80%
External referencesWP_003418198.1 · D5Q0Q3 · MIST4 K1N48_RS12695RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 468 aa (37.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
HisKA: 245-309 aa (65 aa)1HATPase_c: 357-465 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.000000000000823:309:65:64
2 HATPase_c#2
357-465 aa · 109 aa · 23.3% of protein
Raw tokenHATPase_c:357:1.94e-18:465:110:109
  • Raw architecture: HisKA:245:0.000000000000823:309:65:64#HATPase_c:357:1.94e-18:465:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_019427665::NZ_JAGIWO010000033.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6239-8403Genomic interval covered by the local TCS group.
Context group IDGCF_019427665::NZ_JAGIWO010000033.1::G00032
Context members
K1N48_RS12690K1N48_RS12695
Partner locus tags
K1N48_RS12690K1N48_RS12695
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003418198.1Primary protein accession used for annex mappings.
UniProt accessionD5Q0Q3Primary UniProt accession resolved in the annex database.
UniProt IDD5Q0Q3_CLODIDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagK1N48_RS12695Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JAGIWO010000033.1Sequence record reported by the local genomic context database.
Genomic interval6 997-8 403 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 239-8 403 ntGCF_019427665::NZ_JAGIWO010000033.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_019427665::NZ_JAGIWO010000033.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGIWO010000033.1All displayed genes belong to this local TCS context.
Neighborhood span6 239-8 403 nt2 165 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 239 nt8 403 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1737648Run 6 · HK · 296 sequences
Representative sequenceGCF_000155065#QAE_RS0203390Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1737648

Simplified PFAM architecture for HKOC_1737648

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1737648
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0203390

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_019427665
AssemblyASM1942766v1 · Scaffoldhaploid
Genome composition3 970 810 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 47 · RR 48CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key