Gene detail

K1N06_RS19725

Histidine kinase, Hybrid

Clostridioides difficile · GCF_019426845

ClassHKTypeHybridLength798 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_019426845#K1N06_RS19725Stable P2CS identifier used across views.
GenomeGCF_019426845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0484794Run 6 · 30 sequences · id 100% · cov 80%
External referencesWP_330626558.1 · MIST4 K1N06_RS19725RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length798 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 798 aa (51.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa798 aa
HisKA: 290-356 aa (67 aa)1HATPase_c: 404-522 aa (119 aa)2Response_reg: 538-642 aa (105 aa)3Response_reg: 677-794 aa (118 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
290-356 aa · 67 aa · 8.4% of protein
Raw tokenHisKA:290:5.34e-18:356:67:64
2 HATPase_c#2
404-522 aa · 119 aa · 14.9% of protein
Raw tokenHATPase_c:404:4.51e-25:522:120:109
3 Response_reg#3
538-642 aa · 105 aa · 13.2% of protein
Raw tokenResponse_reg:538:1.19e-21:642:105:111
4 Response_reg#4
677-794 aa · 118 aa · 14.8% of protein
Raw tokenResponse_reg:677:9.6e-27:794:118:111
  • Raw architecture: HisKA:290:5.34e-18:356:67:64#HATPase_c:404:4.51e-25:522:120:109#Response_reg:538:1.19e-21:642:105:111#Response_reg:677:9.6e-27:794:118:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_019426845::NZ_JAGIVK010000058.1::G00053
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span15262-17658Genomic interval covered by the local TCS group.
Context group IDGCF_019426845::NZ_JAGIVK010000058.1::G00053
Context members
K1N06_RS19725
Partner locus tags
K1N06_RS19725
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330626558.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagK1N06_RS19725Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JAGIVK010000058.1Sequence record reported by the local genomic context database.
Genomic interval15 262-17 658 nt2 397 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 262-17 658 ntGCF_019426845::NZ_JAGIVK010000058.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_019426845::NZ_JAGIVK010000058.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGIVK010000058.1All displayed genes belong to this local TCS context.
Neighborhood span15 262-17 658 nt2 397 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 262 nt17 658 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0484794Run 6 · HK · 30 sequences
Representative sequenceGCF_000449065#QCK_RS03940Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0484794

Simplified PFAM architecture for HKOC_0484794

PFAM domain coverage: 413 / 852 aa (48.5%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-702 aaResponse_regResponse_reg: 731-847 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
  • Domain count: 4
  • Matched identifier: HKOC_0484794
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449065#QCK_RS03940

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_019426845
AssemblyASM1942684v1 · Scaffoldhaploid
Genome composition4 648 325 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 48 · RR 56CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key