Gene detail

K1N03_RS05380

Histidine kinase, CheA

Clostridioides difficile · GCF_019426635

ClassHKTypeCheALength699 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_019426635#K1N03_RS05380Stable P2CS identifier used across views.
GenomeGCF_019426635Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0772252Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_219686104.1 · MIST4 K1N03_RS05380RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length699 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage441 / 699 aa (63.1%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa699 aa
Hpt: 3-106 aa (104 aa)1H-kinase_dim: 311-372 aa (62 aa)2HATPase_c: 419-558 aa (140 aa)3CheW: 563-697 aa (135 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
3-106 aa · 104 aa · 14.9% of protein
Raw tokenHpt:3:0.00000000000000955:106:104:84
2 H-kinase_dim#2
311-372 aa · 62 aa · 8.9% of protein
Raw tokenH-kinase_dim:311:0.00000000000000438:372:67:67
3 HATPase_c#3
419-558 aa · 140 aa · 20.0% of protein
Raw tokenHATPase_c:419:1.69e-17:558:140:109
4 CheW#4
563-697 aa · 135 aa · 19.3% of protein
Raw tokenCheW:563:1.98e-22:697:136:138
  • Raw architecture: Hpt:3:0.00000000000000955:106:104:84#H-kinase_dim:311:0.00000000000000438:372:67:67#HATPase_c:419:1.69e-17:558:140:109#CheW:563:1.98e-22:697:136:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_019426635::NZ_JAFJTU010000005.1::G00050
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span43436-45535Genomic interval covered by the local TCS group.
Context group IDGCF_019426635::NZ_JAFJTU010000005.1::G00050
Context members
K1N03_RS05380
Partner locus tags
K1N03_RS05380
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_219686104.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagK1N03_RS05380Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JAFJTU010000005.1Sequence record reported by the local genomic context database.
Genomic interval43 436-45 535 nt2 100 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span43 436-45 535 ntGCF_019426635::NZ_JAFJTU010000005.1::G00050

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_019426635::NZ_JAFJTU010000005.1::G00050

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAFJTU010000005.1All displayed genes belong to this local TCS context.
Neighborhood span43 436-45 535 nt2 100 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 436 nt45 535 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0772252Run 6 · HK · 1 sequences
Representative sequenceGCF_019426635#K1N03_RS05380The current gene is the representative for this cluster.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0772252

Simplified PFAM architecture for HKOC_0772252

PFAM domain coverage: 513 / 699 aa (73.4%)

1 aa699 aa
Hpt: 3-104 aaHptP2: 164-240 aaP2H-kinase_dim: 311-372 aaH-kinase_dimHATPase_c: 421-558 aaHATPase_cCheW: 564-697 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[311-372] | HATPase_c[421-558] | CheW[564-697]
  • Domain count: 5
  • Matched identifier: HKOC_0772252
  • Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 311-372 ; HATPase_c 421-558 ; CheW 564-697
Cluster members and taxonomy
Visualization

Representative gene: GCF_019426635#K1N03_RS05380

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_019426635
AssemblyASM1942663v1 · Scaffoldhaploid
Genome composition4 163 949 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key