Gene detail

E1H24_RS10830

Histidine kinase, Classic

Clostridioides difficile · GCF_018885045

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018885045#E1H24_RS10830Stable P2CS identifier used across views.
GenomeGCF_018885045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827968Run 6 · 24 sequences · id 100% · cov 80%
External referencesWP_021408311.1 · MIST4 E1H24_RS10830RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for E1H24_RS10830
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.000000295:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:3.18e-24:341:101:109
  • Raw architecture: HisKA:124:0.000000295:189:66:64#HATPase_c:241:3.18e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018885045::NZ_CP037844.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2228228-2229935Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H24_11070RefSeq proteinWP_021408311.1
Context group IDGCF_018885045::NZ_CP037844.1::G00034
Context members
E1H24_RS10825E1H24_RS10830
Partner locus tags
E1H24_RS10825E1H24_RS10830
Partner old locus tags
E1H24_11065E1H24_11070
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021408311.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H24_RS10830Primary locus identifier stored in the genes table.
Old locus tagE1H24_11070Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP037844.1Sequence record reported by the local genomic context database.
Genomic interval2 228 904-2 229 935 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 228 228-2 229 935 ntGCF_018885045::NZ_CP037844.1::G00034

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018885045::NZ_CP037844.1::G00034

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP037844.1All displayed genes belong to this local TCS context.
Neighborhood span2 228 228-2 229 935 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 228 228 nt2 229 935 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H24_RS10825GCF_018885045#E1H24_RS10825
RROmpR

2 228 228-2 228 914 nt · Forward (+)

Old locus E1H24_11065RefSeq WP_070442099.1
E1H24_RS10830GCF_018885045#E1H24_RS10830
HKClassicCurrent focus

2 228 904-2 229 935 nt · Forward (+)

Old locus E1H24_11070RefSeq WP_021408311.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827968Run 6 · HK · 24 sequences
Representative sequenceGCF_000450785#QO7_RS09755Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827968

Simplified PFAM architecture for HKOC_2827968

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827968
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450785#QO7_RS09755

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 24 over 24 total members. Page 1 / 1.

GCF_000450785#QO7_RS09755 (representative)
QO7_RS09755 · HK · Classic
RefSeq: WP_021408311.1
GCF_000530795#BN175_RS09765
BN175_RS09765 · HK · Classic
RefSeq: WP_021408311.1
GCF_000531785#BN176_RS09690
BN176_RS09690 · HK · Classic
RefSeq: WP_021408311.1
GCF_001971865#BER27_RS10245
BER27_RS10245 · HK · Classic
RefSeq: WP_021408311.1
GCF_002301165#BGU11_RS06750
BGU11_RS06750 · HK · Classic
RefSeq: WP_021408311.1
GCF_002301465#BGU24_RS09600
BGU24_RS09600 · HK · Classic
RefSeq: WP_021408311.1
GCF_002301525#BGU28_RS11645
BGU28_RS11645 · HK · Classic
RefSeq: WP_021408311.1
GCF_002301615#BGU34_RS09155
BGU34_RS09155 · HK · Classic
RefSeq: WP_021408311.1
GCF_002301715#BGU39_RS11010
BGU39_RS11010 · HK · Classic
RefSeq: WP_021408311.1
GCF_002303105#BGV21_RS07200
BGV21_RS07200 · HK · Classic
RefSeq: WP_021408311.1
GCF_002891615#AMR88_RS11465
AMR88_RS11465 · HK · Classic
RefSeq: WP_021408311.1
GCF_002891625#AMR90_RS07165
AMR90_RS07165 · HK · Classic
RefSeq: WP_021408311.1
GCF_002954305#AMR91_RS02030
AMR91_RS02030 · HK · Classic
RefSeq: WP_021408311.1
GCF_004315425#E0P58_RS04440
E0P58_RS04440 · HK · Classic
RefSeq: WP_021408311.1
GCF_004315685#E0P55_RS03330
E0P55_RS03330 · HK · Classic
RefSeq: WP_021408311.1
GCF_005502205#E5N70_RS02040
E5N70_RS02040 · HK · Classic
RefSeq: WP_021408311.1
GCF_015351915#ITI95_RS08100
ITI95_RS08100 · HK · Classic
RefSeq: WP_021408311.1
GCF_018885045#E1H24_RS10830
E1H24_RS10830 · HK · Classic
RefSeq: WP_021408311.1
GCF_023656875#NB460_RS09940
NB460_RS09940 · HK · Classic
RefSeq: WP_021408311.1
GCF_024260125#NMF90_RS10655
NMF90_RS10655 · HK · Classic
RefSeq: WP_021408311.1
GCF_900243105#DBQ00_RS07185
DBQ00_RS07185 · HK · Classic
RefSeq: WP_021408311.1
GCF_900243125#DBQ03_RS07915
DBQ03_RS07915 · HK · Classic
RefSeq: WP_021408311.1
GCF_900687405#E4V63_RS03290
E4V63_RS03290 · HK · Classic
RefSeq: WP_021408311.1
GCF_932185835#QV674_RS12300
QV674_RS12300 · HK · Classic
RefSeq: WP_021408311.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018885045
AssemblyASM1888504v1 · Complete Genomehaploid
Genome composition4 282 853 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 47 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key