1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw token
HisKA:185:0.000000000202:250:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H25_RS10770
Histidine kinase, Classic
Clostridioides difficile · GCF_018885025
ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018885025#E1H25_RS10770Stable P2CS identifier used across views.
GenomeGCF_018885025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa410 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw token
HATPase_c:296:1.14e-24:408:113:109- Raw architecture: HisKA:185:0.000000000202:250:66:64#HATPase_c:296:1.14e-24:408:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018885025::NZ_CP037853.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2367094-2368987Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H25_10895RefSeq proteinWP_021372043.1
Context group ID
GCF_018885025::NZ_CP037853.1::G00031Context members
E1H25_RS10770E1H25_RS10775
Partner locus tags
E1H25_RS10770E1H25_RS10775
Partner old locus tags
E1H25_10895E1H25_10900
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021372043.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H25_RS10770Primary locus identifier stored in the genes table.
Old locus tagE1H25_10895Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP037853.1Sequence record reported by the local genomic context database.
Genomic interval2 367 094-2 368 326 nt1 233 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 367 094-2 368 987 ntGCF_018885025::NZ_CP037853.1::G00031
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018885025::NZ_CP037853.1::G00031Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP037853.1All displayed genes belong to this local TCS context.
Neighborhood span2 367 094-2 368 987 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 367 094 nt2 368 987 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1H25_RS10770GCF_018885025#E1H25_RS10770
HKClassicCurrent focus
2 367 094-2 368 326 nt · Reverse (-)
E1H25_RS10775GCF_018885025#E1H25_RS10775
RROmpR
2 368 316-2 368 987 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449025#QCG_RS09385Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2354500
Simplified PFAM architecture for HKOC_2354500
PFAM domain coverage: 178 / 410 aa (43.4%)
1 aa410 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[185-250] | HATPase_c[297-408]
- Domain count: 2
- Matched identifier: HKOC_2354500
- Positioned domains: HisKA 185-250 ; HATPase_c 297-408
Cluster members and taxonomy
Representative gene: GCF_000449025#QCG_RS09385
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018885025
AssemblyASM1888502v1 · Chromosomehaploid
Genome composition4 261 386 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key