Gene detail

E1H29_RS04735

Histidine kinase, Classic

Clostridioides difficile · GCF_018884965

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018884965#E1H29_RS04735Stable P2CS identifier used across views.
GenomeGCF_018884965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876373Run 6 · 114 sequences · id 100% · cov 80%
External referencesWP_011860966.1 · Q18A16 · MIST4 E1H29_RS04735RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa311 aa
HisKA: 94-156 aa (63 aa)1HATPase_c: 204-310 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw tokenHisKA:94:0.000000107:156:63:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:5.39e-31:310:107:109
  • Raw architecture: HisKA:94:0.000000107:156:63:64#HATPase_c:204:5.39e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018884965::NZ_CP037839.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span990855-992479Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H29_04905RefSeq proteinWP_011860966.1
Context group IDGCF_018884965::NZ_CP037839.1::G00017
Context members
E1H29_RS04730E1H29_RS04735
Partner locus tags
E1H29_RS04730E1H29_RS04735
Partner old locus tags
E1H29_04900E1H29_04905
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011860966.1Primary protein accession used for annex mappings.
UniProt accessionQ18A16Primary UniProt accession resolved in the annex database.
UniProt IDQ18A16_CLOD6Display identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H29_RS04735Primary locus identifier stored in the genes table.
Old locus tagE1H29_04905Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP037839.1Sequence record reported by the local genomic context database.
Genomic interval991 544-992 479 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span990 855-992 479 ntGCF_018884965::NZ_CP037839.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018884965::NZ_CP037839.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP037839.1All displayed genes belong to this local TCS context.
Neighborhood span990 855-992 479 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
990 855 nt992 479 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H29_RS04730GCF_018884965#E1H29_RS04730
RROmpR

990 855-991 547 nt · Forward (+)

Old locus E1H29_04900RefSeq WP_009888625.1
E1H29_RS04735GCF_018884965#E1H29_RS04735
HKClassicCurrent focus

991 544-992 479 nt · Forward (+)

Old locus E1H29_04905RefSeq WP_011860966.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876373Run 6 · HK · 114 sequences
Representative sequenceGCF_000009205#CD630_RS04690Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876373

Simplified PFAM architecture for HKOC_2876373

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876373
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS04690

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 114 total members. Page 1 / 3.

GCF_000009205#CD630_RS04690 (representative)
CD630_RS04690 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000448885#QAU_RS04115
QAU_RS04115 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000449005#QCE_RS04010
QCE_RS04010 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000449405#QEU_RS12695
QEU_RS12695 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000449445#QEY_RS04150
QEY_RS04150 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000449565#QMI_RS04605
QMI_RS04605 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000449625#QMM_RS04340
QMM_RS04340 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000449905#QIC_RS04435
QIC_RS04435 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450185#QK7_RS04845
QK7_RS04845 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450205#QK9_RS04655
QK9_RS04655 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450285#QKG_RS04300
QKG_RS04300 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450325#QKM_RS03990
QKM_RS03990 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450405#QKU_RS04595
QKU_RS04595 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450445#QKY_RS03950
QKY_RS03950 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450685#QMU_RS03915
QMU_RS03915 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450745#QO3_RS04565
QO3_RS04565 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000450945#QQM_RS04230
QQM_RS04230 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000451185#QQ3_RS04640
QQ3_RS04640 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000451425#QOY_RS04310
QOY_RS04310 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000451525#QQC_RS04280
QQC_RS04280 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000451705#QS7_RS14215
QS7_RS14215 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000451725#QS9_RS04280
QS9_RS04280 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000530595#BN185_RS04000
BN185_RS04000 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000531225#BN184_RS04395
BN184_RS04395 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000828225#SE46_RS19790
SE46_RS19790 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000828235#SE44_RS15400
SE44_RS15400 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000828255#SE45_RS19730
SE45_RS19730 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000828325#NX98_RS11355
NX98_RS11355 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000932055#CDIF630_RS04780
CDIF630_RS04780 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_000953275#CD630DERM_RS04785
CD630DERM_RS04785 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_002080065#CDIF630erm_RS04895
CDIF630erm_RS04895 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_002082945#A6J96_RS18520
A6J96_RS18520 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_002301505#BGU27_RS05875
BGU27_RS05875 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_002302085#BGU87_RS01800
BGU87_RS01800 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_002302905#BGV10_RS10920
BGV10_RS10920 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_002303575#BGU68_RS17230
BGU68_RS17230 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_002940905#AWN78_RS15780
AWN78_RS15780 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_003044135#DA089_RS16550
DA089_RS16550 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_003044155#C5H93_RS15110
C5H93_RS15110 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_003313565#CDIF27639_RS04630
CDIF27639_RS04630 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_003597855#DA434_RS04605
DA434_RS04605 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_003932635#EGL77_RS18815
EGL77_RS18815 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_003932645#EGL76_RS15680
EGL76_RS15680 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_004318725#E0R27_RS17320
E0R27_RS17320 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_004319045#E0R34_RS13095
E0R34_RS13095 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_006379355#DA433_RS15950
DA433_RS15950 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_006380835#DA416_RS04690
DA416_RS04690 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_006408335#DA411_RS05160
DA411_RS05160 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_018263895#E1H49_RS14745
E1H49_RS14745 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16
GCF_018884965#E1H29_RS04735
E1H29_RS04735 · HK · Classic
RefSeq: WP_011860966.1
UniProt: Q18A16

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018884965
AssemblyASM1888496v1 · Complete Genomehaploid
Genome composition4 321 901 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 111 · HK 53 · RR 58CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key