Gene detail

E1H37_RS02600

Histidine kinase, Classic

Clostridioides difficile · GCF_018884765

ClassHKTypeClassicLength307 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018884765#E1H37_RS02600Stable P2CS identifier used across views.
GenomeGCF_018884765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2880578Run 6 · 55 sequences · id 100% · cov 80%
External referencesWP_021367517.1 · MIST4 E1H37_RS02600RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length307 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 307 aa (55.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa307 aa
HisKA: 89-151 aa (63 aa)1HATPase_c: 199-306 aa (108 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
89-151 aa · 63 aa · 20.5% of protein
Raw tokenHisKA:89:0.0000000501:151:63:64
2 HATPase_c#2
199-306 aa · 108 aa · 35.2% of protein
Raw tokenHATPase_c:199:8.42e-30:306:108:109
  • Raw architecture: HisKA:89:0.0000000501:151:63:64#HATPase_c:199:8.42e-30:306:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018884765::NZ_CP037818.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span446074-447700Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H37_02630RefSeq proteinWP_021367517.1
Context group IDGCF_018884765::NZ_CP037818.1::G00002
Context members
E1H37_RS02600E1H37_RS02605
Partner locus tags
E1H37_RS02600E1H37_RS02605
Partner old locus tags
E1H37_02630E1H37_02635
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021367517.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H37_RS02600Primary locus identifier stored in the genes table.
Old locus tagE1H37_02630Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP037818.1Sequence record reported by the local genomic context database.
Genomic interval446 074-446 997 nt924 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span446 074-447 700 ntGCF_018884765::NZ_CP037818.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018884765::NZ_CP037818.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP037818.1All displayed genes belong to this local TCS context.
Neighborhood span446 074-447 700 nt1 627 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
446 074 nt447 700 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H37_RS02600GCF_018884765#E1H37_RS02600
HKClassicCurrent focus

446 074-446 997 nt · Reverse (-)

Old locus E1H37_02630RefSeq WP_021367517.1
E1H37_RS02605GCF_018884765#E1H37_RS02605
RROmpR

446 999-447 700 nt · Reverse (-)

Old locus E1H37_02635RefSeq WP_021364204.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2880578Run 6 · HK · 55 sequences
Representative sequenceGCF_000448805#QKI_RS02360Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2880578

Simplified PFAM architecture for HKOC_2880578

PFAM domain coverage: 172 / 307 aa (56.0%)

1 aa307 aa
HisKA: 88-151 aaHisKAHATPase_c: 199-306 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-151] | HATPase_c[199-306]
  • Domain count: 2
  • Matched identifier: HKOC_2880578
  • Positioned domains: HisKA 88-151 ; HATPase_c 199-306
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448805#QKI_RS02360

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018884765
AssemblyASM1888476v1 · Complete Genomehaploid
Genome composition4 240 901 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key