1 HisKA#1
195-255 aa · 61 aa · 14.8% of protein
Raw token
HisKA:195:0.000000000000671:255:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H40_RS04815
Histidine kinase, Classic
Clostridioides difficile · GCF_018884725
ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018884725#E1H40_RS04815Stable P2CS identifier used across views.
GenomeGCF_018884725Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 413 aa (40.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa413 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
302-407 aa · 106 aa · 25.7% of protein
Raw token
HATPase_c:302:1.42e-26:407:107:109- Raw architecture: HisKA:195:0.000000000000671:255:61:64#HATPase_c:302:1.42e-26:407:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018884725::NZ_CP037811.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1003920-1005855Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H40_04955RefSeq proteinWP_003418730.1
Context group ID
GCF_018884725::NZ_CP037811.1::G00012Context members
E1H40_RS04810E1H40_RS04815
Partner locus tags
E1H40_RS04810E1H40_RS04815
Partner old locus tags
E1H40_04950E1H40_04955
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003418730.1Primary protein accession used for annex mappings.
UniProt accessionD5Q1G3Primary UniProt accession resolved in the annex database.
UniProt IDD5Q1G3_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H40_RS04815Primary locus identifier stored in the genes table.
Old locus tagE1H40_04955Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP037811.1Sequence record reported by the local genomic context database.
Genomic interval1 004 614-1 005 855 nt1 242 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 003 920-1 005 855 ntGCF_018884725::NZ_CP037811.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018884725::NZ_CP037811.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP037811.1All displayed genes belong to this local TCS context.
Neighborhood span1 003 920-1 005 855 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 003 920 nt1 005 855 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1H40_RS04810GCF_018884725#E1H40_RS04810
RROmpR
1 003 920-1 004 603 nt · Forward (+)
E1H40_RS04815GCF_018884725#E1H40_RS04815
HKClassicCurrent focus
1 004 614-1 005 855 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164175#HMPREF0220_RS06750Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2328127
Simplified PFAM architecture for HKOC_2328127
PFAM domain coverage: 172 / 413 aa (41.6%)
1 aa413 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[193-255] | HATPase_c[302-410]
- Domain count: 2
- Matched identifier: HKOC_2328127
- Positioned domains: HisKA 193-255 ; HATPase_c 302-410
Cluster members and taxonomy
Representative gene: GCF_000164175#HMPREF0220_RS06750
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018884725
AssemblyASM1888472v1 · Complete Genomehaploid
Genome composition3 936 124 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key