Gene detail

EXW46_RS25005

Histidine kinase, Classic

Bacillus mycoides · GCF_018741505

ClassHKTypeClassicLength496 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018741505#EXW46_RS25005Stable P2CS identifier used across views.
GenomeGCF_018741505Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1499335Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_060751517.1 · A0A125PKV5 · MIST4 EXW46_RS25005RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length496 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 496 aa (48.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa496 aa
HAMP: 192-258 aa (67 aa)1HisKA: 270-334 aa (65 aa)2HATPase_c: 383-492 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
192-258 aa · 67 aa · 13.5% of protein
Raw tokenHAMP:192:8.73e-17:258:67:69
2 HisKA#2
270-334 aa · 65 aa · 13.1% of protein
Raw tokenHisKA:270:0.0000000000000157:334:65:64
3 HATPase_c#3
383-492 aa · 110 aa · 22.2% of protein
Raw tokenHATPase_c:383:8.25e-31:492:110:109
  • Raw architecture: HAMP:192:8.73e-17:258:67:69#HisKA:270:0.0000000000000157:334:65:64#HATPase_c:383:8.25e-31:492:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018741505::NZ_CP036085.1::G00064
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4868265-4870460Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEXW46_25595RefSeq proteinWP_060751517.1
Context group IDGCF_018741505::NZ_CP036085.1::G00064
Context members
EXW46_RS25000EXW46_RS25005
Partner locus tags
EXW46_RS25000EXW46_RS25005
Partner old locus tags
EXW46_25590EXW46_25595
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_060751517.1Primary protein accession used for annex mappings.
UniProt accessionA0A125PKV5Primary UniProt accession resolved in the annex database.
UniProt IDA0A125PKV5_BACMYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEXW46_RS25005Primary locus identifier stored in the genes table.
Old locus tagEXW46_25595Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP036085.1Sequence record reported by the local genomic context database.
Genomic interval4 868 970-4 870 460 nt1 491 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 868 265-4 870 460 ntGCF_018741505::NZ_CP036085.1::G00064

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018741505::NZ_CP036085.1::G00064

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP036085.1All displayed genes belong to this local TCS context.
Neighborhood span4 868 265-4 870 460 nt2 196 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 868 265 nt4 870 460 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EXW46_RS25000GCF_018741505#EXW46_RS25000
RROmpR

4 868 265-4 868 954 nt · Reverse (-)

Old locus EXW46_25590RefSeq WP_002031197.1
EXW46_RS25005GCF_018741505#EXW46_RS25005
HKClassicCurrent focus

4 868 970-4 870 460 nt · Reverse (-)

Old locus EXW46_25595RefSeq WP_060751517.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1499335Run 6 · HK · 6 sequences
Representative sequenceGCF_001541985#AWW70_RS23885Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1499335

Simplified PFAM architecture for HKOC_1499335

PFAM domain coverage: 229 / 496 aa (46.2%)

1 aa496 aa
HAMP: 206-258 aaHAMPHisKA: 270-334 aaHisKAHATPase_c: 383-493 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[206-258] | HisKA[270-334] | HATPase_c[383-493]
  • Domain count: 3
  • Matched identifier: HKOC_1499335
  • Positioned domains: HAMP 206-258 ; HisKA 270-334 ; HATPase_c 383-493
Cluster members and taxonomy
Visualization

Representative gene: GCF_001541985#AWW70_RS23885

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 405 · GCF_018741505
AssemblyASM1874150v1 · Complete Genomehaploid
Genome composition5 490 614 bp · 35,5% GCBacillus mycoides
Signal transduction countsGenes 138 · HK 75 · RR 63CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key