Gene detail

KK112_RS07965

Histidine kinase, Classic

Clostridioides difficile · GCF_018603475

ClassHKTypeClassicLength618 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_018603475#KK112_RS07965Stable P2CS identifier used across views.
GenomeGCF_018603475Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0977619Run 6 · 276 sequences · id 100% · cov 80%
External referencesWP_003420176.1 · D5Q6Q0 · MIST4 KK112_RS07965RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_4HisKAHATPase_c
Protein length618 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 618 aa (46.9%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for KK112_RS07965
Domain-by-domain annotation3 items
1 PAS_4#1
246-354 aa · 109 aa · 17.6% of protein
Raw tokenPAS_4:246:0.00000000227:354:115:110
2 HisKA#2
363-432 aa · 70 aa · 11.3% of protein
Raw tokenHisKA:363:4.28e-16:432:70:64
3 HATPase_c#3
479-589 aa · 111 aa · 18.0% of protein
Raw tokenHATPase_c:479:5.33e-28:589:111:109
  • Raw architecture: PAS_4:246:0.00000000227:354:115:110#HisKA:363:4.28e-16:432:70:64#HATPase_c:479:5.33e-28:589:111:109
  • Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_018603475::NZ_CP075685.1::G00021
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1685242-1687098Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKK112_07965RefSeq proteinWP_003420176.1
Context group IDGCF_018603475::NZ_CP075685.1::G00021
Context members
KK112_RS07965
Partner locus tags
KK112_RS07965
Partner old locus tags
KK112_07965
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003420176.1Primary protein accession used for annex mappings.
UniProt accessionD5Q6Q0Primary UniProt accession resolved in the annex database.
UniProt IDD5Q6Q0_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKK112_RS07965Primary locus identifier stored in the genes table.
Old locus tagKK112_07965Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP075685.1Sequence record reported by the local genomic context database.
Genomic interval1 685 242-1 687 098 nt1 857 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 685 242-1 687 098 ntGCF_018603475::NZ_CP075685.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018603475::NZ_CP075685.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP075685.1All displayed genes belong to this local TCS context.
Neighborhood span1 685 242-1 687 098 nt1 857 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 685 242 nt1 687 098 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

KK112_RS07965GCF_018603475#KK112_RS07965
HKClassicCurrent focus

1 685 242-1 687 098 nt · Forward (+)

Old locus KK112_07965RefSeq WP_003420176.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0977619Run 6 · HK · 276 sequences
Representative sequenceGCF_000164175#HMPREF0220_RS03900Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0977619

Simplified PFAM architecture for HKOC_0977619

PFAM domain coverage: 290 / 618 aa (46.9%)

1 aa618 aa
PAS_4: 246-354 aaPAS_4HisKA: 363-432 aaHisKAHATPase_c: 479-589 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[246-354] | HisKA[363-432] | HATPase_c[479-589]
  • Domain count: 3
  • Matched identifier: HKOC_0977619
  • Positioned domains: PAS_4 246-354 ; HisKA 363-432 ; HATPase_c 479-589
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164175#HMPREF0220_RS03900

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 276 total members. Page 1 / 6.

GCF_000164175#HMPREF0220_RS03900 (representative)
HMPREF0220_RS03900 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_000164655#HMPREF0219_RS06360
HMPREF0219_RS06360 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_000210435#CDM120_RS08255
CDM120_RS08255 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_000499505#BN164_RS07165
BN164_RS07165 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_000582865#BN165_RS07315
BN165_RS07315 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_001050575#BN163_RS07410
BN163_RS07410 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_001972065#BER35_RS08440
BER35_RS08440 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_001972115#BER34_RS11440
BER34_RS11440 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_002301695#BGU20_RS03565
BGU20_RS03565 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_002302685#BGU93_RS04385
BGU93_RS04385 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_002303305#BGU53_RS08500
BGU53_RS08500 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_002352505#V439_RS16480
V439_RS16480 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_002412385#V438_RS12555
V438_RS12555 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_002946515#C4E25_RS08015
C4E25_RS08015 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_002946535#C4E42_RS11175
C4E42_RS11175 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_002946555#C4E26_RS08015
C4E26_RS08015 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_003482165#CDIF29020_RS08145
CDIF29020_RS08145 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_003482365#CDIF29747_RS08015
CDIF29747_RS08015 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_003697245#EBL91_RS07805
EBL91_RS07805 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_004318565#E0Q96_RS07015
E0Q96_RS07015 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_004318785#E0Q93_RS03920
E0Q93_RS03920 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_008579085#F6C11_RS02365
F6C11_RS02365 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_009362915#FTB24_RS11045
FTB24_RS11045 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_012952655#HCN89_RS08775
HCN89_RS08775 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_015351855#ITI91_RS08275
ITI91_RS08275 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_015352255#ITJ05_RS11670
ITJ05_RS11670 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016766955#JMW53_RS16100
JMW53_RS16100 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016766975#JMW50_RS04890
JMW50_RS04890 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016766995#JMW52_RS12570
JMW52_RS12570 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016767015#JMW49_RS00645
JMW49_RS00645 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016767035#JMW55_RS15455
JMW55_RS15455 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016767055#JMW51_RS12880
JMW51_RS12880 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016767095#JMW48_RS07110
JMW48_RS07110 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016767115#JMW47_RS03690
JMW47_RS03690 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_016767135#JMW46_RS17315
JMW46_RS17315 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_017592625#J5O10_RS07840
J5O10_RS07840 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_018603395#KK111_RS07980
KK111_RS07980 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_018603455#KK110_RS07975
KK110_RS07975 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_018603475#KK112_RS07965
KK112_RS07965 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_018884725#E1H40_RS07765
E1H40_RS07765 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_019427665#K1N48_RS10245
K1N48_RS10245 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_019427725#K1N54_RS05445
K1N54_RS05445 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_020297505#LA365_RS04885
LA365_RS04885 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_021283625#LWE91_RS04380
LWE91_RS04380 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_021283665#LWF03_RS01310
LWF03_RS01310 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_021283685#LWE71_RS16010
LWE71_RS16010 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_021283745#LWE78_RS01245
LWE78_RS01245 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_021283845#LWG76_RS16430
LWG76_RS16430 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_021283885#LWE86_RS02480
LWE86_RS02480 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0
GCF_021284015#LWE81_RS01635
LWE81_RS01635 · HK · Classic
RefSeq: WP_003420176.1
UniProt: D5Q6Q0

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018603475
AssemblyASM1860347v1 · Complete Genomehaploid
Genome composition3 998 712 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key