1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw token
HisKA_3:188:5.14e-21:253:67:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
KK112_RS06375
Histidine kinase, Classic
Clostridioides difficile · GCF_018603475
ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018603475#KK112_RS06375Stable P2CS identifier used across views.
GenomeGCF_018603475Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw token
HATPase_c:294:0.00000000132:378:104:109- Raw architecture: HisKA_3:188:5.14e-21:253:67:68#HATPase_c:294:0.00000000132:378:104:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018603475::NZ_CP075685.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1329872-1331675Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKK112_06375RefSeq proteinWP_003424698.1
Context group ID
GCF_018603475::NZ_CP075685.1::G00016Context members
KK112_RS06370KK112_RS06375
Partner locus tags
KK112_RS06370KK112_RS06375
Partner old locus tags
KK112_06370KK112_06375
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003424698.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX3GVW1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX3GVW1_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagKK112_RS06375Primary locus identifier stored in the genes table.
Old locus tagKK112_06375Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP075685.1Sequence record reported by the local genomic context database.
Genomic interval1 330 512-1 331 675 nt1 164 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 329 872-1 331 675 ntGCF_018603475::NZ_CP075685.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018603475::NZ_CP075685.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP075685.1All displayed genes belong to this local TCS context.
Neighborhood span1 329 872-1 331 675 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 329 872 nt1 331 675 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
KK112_RS06370GCF_018603475#KK112_RS06370
RRNarL
1 329 872-1 330 519 nt · Reverse (-)
KK112_RS06375GCF_018603475#KK112_RS06375
HKClassicCurrent focus
1 330 512-1 331 675 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0206215Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2550121
Simplified PFAM architecture for HKOC_2550121
PFAM domain coverage: 150 / 387 aa (38.8%)
1 aa387 aa
HisKA_3HATPase_c
- Simplified architecture: HisKA_3 + HATPase_c
- Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
- Domain count: 2
- Matched identifier: HKOC_2550121
- Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0206215
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018603475
AssemblyASM1860347v1 · Complete Genomehaploid
Genome composition3 998 712 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key