1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw token
HisKA:182:0.0000000000000118:240:59:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
KK110_RS02755
Histidine kinase, Classic
Clostridioides difficile · GCF_018603455
ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018603455#KK110_RS02755Stable P2CS identifier used across views.
GenomeGCF_018603455Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw token
HATPase_c:293:9.9e-19:391:100:109- Raw architecture: HisKA:182:0.0000000000000118:240:59:64#HATPase_c:293:9.9e-19:391:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018603455::NZ_CP075683.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span520700-522543Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKK110_02755RefSeq proteinWP_003417468.1
Context group ID
GCF_018603455::NZ_CP075683.1::G00002Context members
KK110_RS02755KK110_RS02760
Partner locus tags
KK110_RS02755KK110_RS02760
Partner old locus tags
KK110_02755KK110_02760
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003417468.1Primary protein accession used for annex mappings.
UniProt accessionD5PZZ6Primary UniProt accession resolved in the annex database.
UniProt IDD5PZZ6_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagKK110_RS02755Primary locus identifier stored in the genes table.
Old locus tagKK110_02755Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP075683.1Sequence record reported by the local genomic context database.
Genomic interval520 700-521 881 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span520 700-522 543 ntGCF_018603455::NZ_CP075683.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018603455::NZ_CP075683.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP075683.1All displayed genes belong to this local TCS context.
Neighborhood span520 700-522 543 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
520 700 nt522 543 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
KK110_RS02755GCF_018603455#KK110_RS02755
HKClassicCurrent focus
520 700-521 881 nt · Reverse (-)
KK110_RS02760GCF_018603455#KK110_RS02760
RROmpR
521 881-522 543 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0202145Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2503303
Simplified PFAM architecture for HKOC_2503303
PFAM domain coverage: 162 / 393 aa (41.2%)
1 aa393 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[179-240] | HATPase_c[292-391]
- Domain count: 2
- Matched identifier: HKOC_2503303
- Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0202145
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018603455
AssemblyASM1860345v1 · Complete Genomehaploid
Genome composition3 998 707 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key