1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw token
HisKA:94:0.000000179:156:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
KK111_RS04525
Histidine kinase, Classic
Clostridioides difficile · GCF_018603395
ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018603395#KK111_RS04525Stable P2CS identifier used across views.
GenomeGCF_018603395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa311 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw token
HATPase_c:204:8.4e-31:310:107:109- Raw architecture: HisKA:94:0.000000179:156:63:64#HATPase_c:204:8.4e-31:310:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018603395::NZ_CP075684.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span929039-930663Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKK111_04525RefSeq proteinWP_003418502.1
Context group ID
GCF_018603395::NZ_CP075684.1::G00011Context members
KK111_RS04520KK111_RS04525
Partner locus tags
KK111_RS04520KK111_RS04525
Partner old locus tags
KK111_04520KK111_04525
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003418502.1Primary protein accession used for annex mappings.
UniProt accessionD5Q150Primary UniProt accession resolved in the annex database.
UniProt IDD5Q150_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagKK111_RS04525Primary locus identifier stored in the genes table.
Old locus tagKK111_04525Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP075684.1Sequence record reported by the local genomic context database.
Genomic interval929 728-930 663 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span929 039-930 663 ntGCF_018603395::NZ_CP075684.1::G00011
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018603395::NZ_CP075684.1::G00011Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP075684.1All displayed genes belong to this local TCS context.
Neighborhood span929 039-930 663 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
929 039 nt930 663 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
KK111_RS04520GCF_018603395#KK111_RS04520
RROmpR
929 039-929 731 nt · Forward (+)
KK111_RS04525GCF_018603395#KK111_RS04525
HKClassicCurrent focus
929 728-930 663 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0204125Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2876393
Simplified PFAM architecture for HKOC_2876393
PFAM domain coverage: 170 / 311 aa (54.7%)
1 aa311 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[93-155] | HATPase_c[204-310]
- Domain count: 2
- Matched identifier: HKOC_2876393
- Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0204125
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018603395
AssemblyASM1860339v1 · Complete Genomehaploid
Genome composition3 998 618 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key