1 HAMP#1
198-269 aa · 72 aa · 14.1% of protein
Raw token
HAMP:198:0.0000000000748:269:72:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
KH076_RS00255
Histidine kinase, Classic
Streptococcus sp. · GCF_018382235
ClassHKTypeClassicLength509 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018382235#KH076_RS00255Stable P2CS identifier used across views.
GenomeGCF_018382235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length509 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 509 aa (47.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa509 aa
Domain-by-domain annotation3 items
2 HisKA#2
273-333 aa · 61 aa · 12.0% of protein
Raw token
HisKA:273:0.00000000000000899:333:61:643 HATPase_c#3
389-498 aa · 110 aa · 21.6% of protein
Raw token
HATPase_c:389:1.15e-28:498:110:109- Raw architecture: HAMP:198:0.0000000000748:269:72:69#HisKA:273:0.00000000000000899:333:61:64#HATPase_c:389:1.15e-28:498:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018382235::NZ_JAGZQI010000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span53203-55418Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKH076_00255RefSeq proteinWP_293919472.1
Context group ID
GCF_018382235::NZ_JAGZQI010000001.1::G00002Context members
KH076_RS00255KH076_RS00260
Partner locus tags
KH076_RS00255KH076_RS00260
Partner old locus tags
KH076_00255KH076_00260
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_293919472.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagKH076_RS00255Primary locus identifier stored in the genes table.
Old locus tagKH076_00255Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAGZQI010000001.1Sequence record reported by the local genomic context database.
Genomic interval53 203-54 732 nt1 530 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span53 203-55 418 ntGCF_018382235::NZ_JAGZQI010000001.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018382235::NZ_JAGZQI010000001.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGZQI010000001.1All displayed genes belong to this local TCS context.
Neighborhood span53 203-55 418 nt2 216 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
53 203 nt55 418 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
KH076_RS00255GCF_018382235#KH076_RS00255
HKClassicCurrent focus
53 203-54 732 nt · Reverse (-)
KH076_RS00260GCF_018382235#KH076_RS00260
RROmpR
54 729-55 418 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_018382235#KH076_RS00255The current gene is the representative for this cluster.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1434405
Simplified PFAM architecture for HKOC_1434405
PFAM domain coverage: 373 / 509 aa (73.3%)
1 aa509 aa
ArlS_NHAMPHisKAHATPase_c
- Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
- Raw architecture: ArlS_N[43-192] | HAMP[218-269] | HisKA[274-333] | HATPase_c[388-498]
- Domain count: 4
- Matched identifier: HKOC_1434405
- Positioned domains: ArlS_N 43-192 ; HAMP 218-269 ; HisKA 274-333 ; HATPase_c 388-498
Cluster members and taxonomy
Representative gene: GCF_018382235#KH076_RS00255
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 306 · GCF_018382235
AssemblyASM1838223v1 · Contighaploid
Genome composition2 083 171 bp · 39,5% GCStreptococcus sp.
Signal transduction countsGenes 22 · HK 11 · RR 11CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key