Gene detail

E1H43_RS15945

Histidine kinase, Classic

Clostridioides difficile · GCF_018264015

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264015#E1H43_RS15945Stable P2CS identifier used across views.
GenomeGCF_018264015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503302Run 6 · 106 sequences · id 100% · cov 80%
External referencesWP_009901933.1 · A0AB74QCR7 · MIST4 E1H43_RS15945RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
HisKA: 182-240 aa (59 aa)1HATPase_c: 293-391 aa (99 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw tokenHisKA:182:0.0000000000000323:240:59:64
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw tokenHATPase_c:293:2.43e-18:391:100:109
  • Raw architecture: HisKA:182:0.0000000000000323:240:59:64#HATPase_c:293:2.43e-18:391:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018264015::NZ_SMNJ01000001.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3562333-3564176Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H43_16280RefSeq proteinWP_009901933.1
Context group IDGCF_018264015::NZ_SMNJ01000001.1::G00053
Context members
E1H43_RS15940E1H43_RS15945
Partner locus tags
E1H43_RS15940E1H43_RS15945
Partner old locus tags
E1H43_16275E1H43_16280
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009901933.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QCR7Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QCR7_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H43_RS15945Primary locus identifier stored in the genes table.
Old locus tagE1H43_16280Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNJ01000001.1Sequence record reported by the local genomic context database.
Genomic interval3 562 995-3 564 176 nt1 182 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 562 333-3 564 176 ntGCF_018264015::NZ_SMNJ01000001.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018264015::NZ_SMNJ01000001.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNJ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span3 562 333-3 564 176 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 562 333 nt3 564 176 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H43_RS15940GCF_018264015#E1H43_RS15940
RROmpR

3 562 333-3 562 995 nt · Forward (+)

Old locus E1H43_16275RefSeq WP_009901935.1
E1H43_RS15945GCF_018264015#E1H43_RS15945
HKClassicCurrent focus

3 562 995-3 564 176 nt · Forward (+)

Old locus E1H43_16280RefSeq WP_009901933.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503302Run 6 · HK · 106 sequences
Representative sequenceGCF_000155025#UAB_RS0203495Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503302

Simplified PFAM architecture for HKOC_2503302

PFAM domain coverage: 162 / 393 aa (41.2%)

1 aa393 aa
HisKA: 179-240 aaHisKAHATPase_c: 292-391 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[179-240] | HATPase_c[292-391]
  • Domain count: 2
  • Matched identifier: HKOC_2503302
  • Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0203495

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 106 total members. Page 1 / 3.

GCF_000155025#UAB_RS0203495 (representative)
UAB_RS0203495 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000449025#QCG_RS02830
QCG_RS02830 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000449065#QCK_RS03985
QCK_RS03985 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000449305#QEK_RS03165
QEK_RS03165 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000449385#QES_RS03595
QES_RS03595 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000449465#QG1_RS03485
QG1_RS03485 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000449645#QGE_RS03260
QGE_RS03260 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000450725#QMY_RS02645
QMY_RS02645 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000451305#QEE_RS02745
QEE_RS02745 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000451585#QQW_RS02510
QQW_RS02510 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000452065#QUS_RS02805
QUS_RS02805 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_000452405#QE1_RS02710
QE1_RS02710 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_001972185#BER44_RS03645
BER44_RS03645 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002300935#BGT95_RS04990
BGT95_RS04990 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002301095#BGU07_RS09235
BGU07_RS09235 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002301405#BGU19_RS19105
BGU19_RS19105 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002301855#BGU48_RS19205
BGU48_RS19205 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002302145#BGU91_RS01760
BGU91_RS01760 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002303075#BGV20_RS16865
BGV20_RS16865 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002303365#BGU56_RS13835
BGU56_RS13835 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002303505#BGU65_RS06750
BGU65_RS06750 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_002303525#BGU66_RS05540
BGU66_RS05540 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_003862575#EGM15_RS13625
EGM15_RS13625 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_003862815#EGL98_RS09820
EGL98_RS09820 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_004315785#E0P73_RS12820
E0P73_RS12820 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_004684515#E5F39_RS11455
E5F39_RS11455 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_004684595#E5F35_RS07230
E5F35_RS07230 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_004684665#E5F32_RS07100
E5F32_RS07100 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_006380955#DA423_RS03435
DA423_RS03435 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_006381075#DA431_RS02835
DA431_RS02835 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_007000825#D1N74_RS13830
D1N74_RS13830 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_015238635#GLV80_RS16440
GLV80_RS16440 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_015352055#ITJ07_RS02795
ITJ07_RS02795 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_015352395#ITJ30_RS20545
ITJ30_RS20545 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_016985475#I6K75_RS09330
I6K75_RS09330 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_018264015#E1H43_RS15945
E1H43_RS15945 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_018884785#E1H38_RS02685
E1H38_RS02685 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_018884845#E1H34_RS02805
E1H34_RS02805 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_018884905#E1H31_RS02800
E1H31_RS02800 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_018885025#E1H25_RS16510
E1H25_RS16510 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_019426845#K1N06_RS22855
K1N06_RS22855 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_019427025#K1N19_RS20875
K1N19_RS20875 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_019427345#K1N32_RS20330
K1N32_RS20330 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_019427905#K1N58_RS20595
K1N58_RS20595 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_019428005#K1N60_RS20665
K1N60_RS20665 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_019880625#H3B84_RS13225
H3B84_RS13225 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_028596345#PSM50_RS11135
PSM50_RS11135 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_028596355#PSL93_RS16805
PSL93_RS16805 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_028596415#PSM41_RS10610
PSM41_RS10610 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7
GCF_028596425#PSM54_RS14620
PSM54_RS14620 · HK · Classic
RefSeq: WP_009901933.1
UniProt: A0AB74QCR7

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264015
AssemblyASM1826401v1 · Contighaploid
Genome composition4 419 141 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key