1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw token
HAMP:212:0.00000636:279:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H43_RS13615
Histidine kinase, Classic
Clostridioides difficile · GCF_018264015
ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264015#E1H43_RS13615Stable P2CS identifier used across views.
GenomeGCF_018264015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
Domain-by-domain annotation3 items
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw token
HisKA:289:3.41e-17:347:59:643 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw token
HATPase_c:395:2.81e-27:495:106:109- Raw architecture: HAMP:212:0.00000636:279:68:69#HisKA:289:3.41e-17:347:59:64#HATPase_c:395:2.81e-27:495:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018264015::NZ_SMNJ01000001.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3011296-3013489Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H43_13875RefSeq proteinWP_021370209.1
Context group ID
GCF_018264015::NZ_SMNJ01000001.1::G00042Context members
E1H43_RS13615E1H43_RS13620
Partner locus tags
E1H43_RS13615E1H43_RS13620
Partner old locus tags
E1H43_13875E1H43_13880
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021370209.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H43_RS13615Primary locus identifier stored in the genes table.
Old locus tagE1H43_13875Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNJ01000001.1Sequence record reported by the local genomic context database.
Genomic interval3 011 296-3 012 783 nt1 488 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 011 296-3 013 489 ntGCF_018264015::NZ_SMNJ01000001.1::G00042
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018264015::NZ_SMNJ01000001.1::G00042Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNJ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span3 011 296-3 013 489 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 011 296 nt3 013 489 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1H43_RS13615GCF_018264015#E1H43_RS13615
HKClassicCurrent focus
3 011 296-3 012 783 nt · Reverse (-)
E1H43_RS13620GCF_018264015#E1H43_RS13620
RROmpR
3 012 785-3 013 489 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449025#QCG_RS06020Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1504520
Simplified PFAM architecture for HKOC_1504520
PFAM domain coverage: 161 / 495 aa (32.5%)
1 aa495 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[287-347] | HATPase_c[395-494]
- Domain count: 2
- Matched identifier: HKOC_1504520
- Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Representative gene: GCF_000449025#QCG_RS06020
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264015
AssemblyASM1826401v1 · Contighaploid
Genome composition4 419 141 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key