Gene detail

E1H43_RS10230

Response regulator OmpR family

Clostridioides difficile · GCF_018264015

ClassRRTypeOmpRLength223 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264015#E1H43_RS10230Stable P2CS identifier used across views.
GenomeGCF_018264015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1587374Run 7 · 564 sequences · id 100% · cov 80%
External referencesWP_004454472.1 · A0AB74QEK7 · MIST4 E1H43_RS10230RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length223 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage184 / 223 aa (82.5%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa223 aa
Response_reg: 3-111 aa (109 aa)1Trans_reg_C: 146-220 aa (75 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
3-111 aa · 109 aa · 48.9% of protein
Raw tokenResponse_reg:3:3.19e-34:111:110:111
2 Trans_reg_C#2
146-220 aa · 75 aa · 33.6% of protein
Raw tokenTrans_reg_C:146:5.7e-24:220:76:77
  • Raw architecture: Response_reg:3:3.19e-34:111:110:111#Trans_reg_C:146:5.7e-24:220:76:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018264015::NZ_SMNJ01000001.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2270561-2272454Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H43_10400RefSeq proteinWP_004454472.1
Context group IDGCF_018264015::NZ_SMNJ01000001.1::G00031
Context members
E1H43_RS10225E1H43_RS10230
Partner locus tags
E1H43_RS10225E1H43_RS10230
Partner old locus tags
E1H43_10395E1H43_10400
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454472.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QEK7Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QEK7_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H43_RS10230Primary locus identifier stored in the genes table.
Old locus tagE1H43_10400Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNJ01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 271 783-2 272 454 nt672 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 270 561-2 272 454 ntGCF_018264015::NZ_SMNJ01000001.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018264015::NZ_SMNJ01000001.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNJ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 270 561-2 272 454 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 270 561 nt2 272 454 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H43_RS10225GCF_018264015#E1H43_RS10225
HKClassic

2 270 561-2 271 793 nt · Reverse (-)

Old locus E1H43_10395RefSeq WP_021372043.1
E1H43_RS10230GCF_018264015#E1H43_RS10230
RROmpRCurrent focus

2 271 783-2 272 454 nt · Reverse (-)

Old locus E1H43_10400RefSeq WP_004454472.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1587374Run 7 · RR · 564 sequences
Representative sequenceGCF_000155025#UAB_RS0209655Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1587374

Simplified PFAM architecture for RROC_1587374

PFAM domain coverage: 184 / 223 aa (82.5%)

1 aa223 aa
Response_reg: 3-111 aaResponse_regResponse_reg: 3-111 aaResponse_regTrans_reg_C: 146-220 aaTrans_reg_CTrans_reg_C: 146-220 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[3-111] | Trans_reg_C[146-220]
  • Domain count: 2
  • Matched identifier: RROC_1587374
  • Positioned domains: Response_reg 3-111 ; Response_reg 3-111 ; Trans_reg_C 146-220 ; Trans_reg_C 146-220
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0209655

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264015
AssemblyASM1826401v1 · Contighaploid
Genome composition4 419 141 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key