1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw token
HisKA:457:0.0000000000000203:524:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H43_RS06955
Histidine kinase, Classic
Clostridioides difficile · GCF_018264015
ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264015#E1H43_RS06955Stable P2CS identifier used across views.
GenomeGCF_018264015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa686 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw token
HATPase_c:570:0.00000000000196:663:98:109- Raw architecture: HisKA:457:0.0000000000000203:524:68:64#HATPase_c:570:0.00000000000196:663:98:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018264015::NZ_SMNJ01000001.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1586568-1589516Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H43_07040RefSeq proteinWP_009897457.1
Context group ID
GCF_018264015::NZ_SMNJ01000001.1::G00021Context members
E1H43_RS06950E1H43_RS06955
Partner locus tags
E1H43_RS06950E1H43_RS06955
Partner old locus tags
E1H43_07030E1H43_07040
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009897457.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74Q9S7Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74Q9S7_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H43_RS06955Primary locus identifier stored in the genes table.
Old locus tagE1H43_07040Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNJ01000001.1Sequence record reported by the local genomic context database.
Genomic interval1 587 456-1 589 516 nt2 061 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 586 568-1 589 516 ntGCF_018264015::NZ_SMNJ01000001.1::G00021
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018264015::NZ_SMNJ01000001.1::G00021Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNJ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 586 568-1 589 516 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 586 568 nt1 589 516 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1H43_RS06950GCF_018264015#E1H43_RS06950
RROmpR
1 586 568-1 587 260 nt · Forward (+)
E1H43_RS06955GCF_018264015#E1H43_RS06955
HKClassicCurrent focus
1 587 456-1 589 516 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS12360Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0800915
Simplified PFAM architecture for HKOC_0800915
PFAM domain coverage: 160 / 686 aa (23.3%)
1 aa686 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[457-524] | HATPase_c[571-662]
- Domain count: 2
- Matched identifier: HKOC_0800915
- Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS12360
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264015
AssemblyASM1826401v1 · Contighaploid
Genome composition4 419 141 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key