1 HAMP#1
145-212 aa · 68 aa · 15.5% of protein
Raw token
HAMP:145:0.00000497:212:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H43_RS01275
Histidine kinase, Classic
Clostridioides difficile · GCF_018264015
ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264015#E1H43_RS01275Stable P2CS identifier used across views.
GenomeGCF_018264015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 440 aa (48.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
233-297 aa · 65 aa · 14.8% of protein
Raw token
HisKA:233:0.00000483:297:65:643 HATPase_c#3
343-420 aa · 78 aa · 17.7% of protein
Raw token
HATPase_c:343:0.00000514:420:90:109- Raw architecture: HAMP:145:0.00000497:212:68:69#HisKA:233:0.00000483:297:65:64#HATPase_c:343:0.00000514:420:90:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018264015::NZ_SMNJ01000001.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span282564-284544Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H43_01285RefSeq proteinWP_021372735.1
Context group ID
GCF_018264015::NZ_SMNJ01000001.1::G00004Context members
E1H43_RS01270E1H43_RS01275
Partner locus tags
E1H43_RS01270E1H43_RS01275
Partner old locus tags
E1H43_01280E1H43_01285
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021372735.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H43_RS01275Primary locus identifier stored in the genes table.
Old locus tagE1H43_01285Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNJ01000001.1Sequence record reported by the local genomic context database.
Genomic interval283 222-284 544 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span282 564-284 544 ntGCF_018264015::NZ_SMNJ01000001.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018264015::NZ_SMNJ01000001.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNJ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span282 564-284 544 nt1 981 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
282 564 nt284 544 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1H43_RS01270GCF_018264015#E1H43_RS01270
RROmpR
282 564-283 217 nt · Forward (+)
E1H43_RS01275GCF_018264015#E1H43_RS01275
HKClassicCurrent focus
283 222-284 544 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448965#QCA_RS16925Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2072075
Simplified PFAM architecture for HKOC_2072075
PFAM domain coverage: 143 / 440 aa (32.5%)
1 aa440 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[234-297] | HATPase_c[343-421]
- Domain count: 2
- Matched identifier: HKOC_2072075
- Positioned domains: HisKA 234-297 ; HATPase_c 343-421
Cluster members and taxonomy
Representative gene: GCF_000448965#QCA_RS16925
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264015
AssemblyASM1826401v1 · Contighaploid
Genome composition4 419 141 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key