1 HAMP#1
6-74 aa · 69 aa · 16.1% of protein
Raw token
HAMP:6:0.000000849:74:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H50_RS15110
Histidine kinase, Classic
Clostridioides difficile · GCF_018264005
ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264005#E1H50_RS15110Stable P2CS identifier used across views.
GenomeGCF_018264005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPPAS_9HisKAHATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage340 / 429 aa (79.3%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa429 aa
Domain-by-domain annotation4 items
2 PAS_9#2
96-195 aa · 100 aa · 23.3% of protein
Raw token
PAS_9:96:0.00000124:195:103:1023 HisKA#3
202-268 aa · 67 aa · 15.6% of protein
Raw token
HisKA:202:3.14e-18:268:67:644 HATPase_c#4
319-422 aa · 104 aa · 24.2% of protein
Raw token
HATPase_c:319:3.66e-30:422:104:109- Raw architecture: HAMP:6:0.000000849:74:69:69#PAS_9:96:0.00000124:195:103:102#HisKA:202:3.14e-18:268:67:64#HATPase_c:319:3.66e-30:422:104:109
- Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018264005::NZ_SMNN01000001.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3251834-3253844Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H50_15495RefSeq proteinWP_016728477.1
Context group ID
GCF_018264005::NZ_SMNN01000001.1::G00048Context members
E1H50_RS15110E1H50_RS15115
Partner locus tags
E1H50_RS15110E1H50_RS15115
Partner old locus tags
E1H50_15495E1H50_15500
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_016728477.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H50_RS15110Primary locus identifier stored in the genes table.
Old locus tagE1H50_15495Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNN01000001.1Sequence record reported by the local genomic context database.
Genomic interval3 251 834-3 253 123 nt1 290 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 251 834-3 253 844 ntGCF_018264005::NZ_SMNN01000001.1::G00048
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018264005::NZ_SMNN01000001.1::G00048Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNN01000001.1All displayed genes belong to this local TCS context.
Neighborhood span3 251 834-3 253 844 nt2 011 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 251 834 nt3 253 844 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1H50_RS15110GCF_018264005#E1H50_RS15110
HKClassicCurrent focus
3 251 834-3 253 123 nt · Reverse (-)
E1H50_RS15115GCF_018264005#E1H50_RS15115
RROmpR
3 253 152-3 253 844 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000242355#MUI_RS0100685Use this link to inspect the representative gene detail.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2180370
Simplified PFAM architecture for HKOC_2180370
PFAM domain coverage: 321 / 429 aa (74.8%)
1 aa429 aa
HAMPPASHisKAHATPase_c
- Simplified architecture: HAMP + PAS + HisKA + HATPase_c
- Raw architecture: HAMP[33-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
- Domain count: 4
- Matched identifier: HKOC_2180370
- Positioned domains: HAMP 33-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Representative gene: GCF_000242355#MUI_RS0100685
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264005
AssemblyASM1826400v1 · Contighaploid
Genome composition4 265 397 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key