Gene detail

E1H50_RS14810

Response regulator OmpR family

Clostridioides difficile · GCF_018264005

ClassRRTypeOmpRLength238 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264005#E1H50_RS14810Stable P2CS identifier used across views.
GenomeGCF_018264005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0932517Run 7 · 2174 sequences · id 100% · cov 80%
External referencesWP_003431132.1 · A0A069AJS3 · MIST4 E1H50_RS14810RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length238 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage186 / 238 aa (78.2%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for E1H50_RS14810
Domain-by-domain annotation2 items
1 Response_reg#1
6-115 aa · 110 aa · 46.2% of protein
Raw tokenResponse_reg:6:1.29e-33:115:111:111
2 Trans_reg_C#2
160-235 aa · 76 aa · 31.9% of protein
Raw tokenTrans_reg_C:160:6.26e-30:235:77:77
  • Raw architecture: Response_reg:6:1.29e-33:115:111:111#Trans_reg_C:160:6.26e-30:235:77:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018264005::NZ_SMNN01000001.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3183591-3186615Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H50_15195RefSeq proteinWP_003431132.1
Context group IDGCF_018264005::NZ_SMNN01000001.1::G00046
Context members
E1H50_RS14805E1H50_RS14810
Partner locus tags
E1H50_RS14805E1H50_RS14810
Partner old locus tags
E1H50_15190E1H50_15195
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003431132.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AJS3Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AJS3_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H50_RS14810Primary locus identifier stored in the genes table.
Old locus tagE1H50_15195Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNN01000001.1Sequence record reported by the local genomic context database.
Genomic interval3 185 899-3 186 615 nt717 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 183 591-3 186 615 ntGCF_018264005::NZ_SMNN01000001.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018264005::NZ_SMNN01000001.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNN01000001.1All displayed genes belong to this local TCS context.
Neighborhood span3 183 591-3 186 615 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 183 591 nt3 186 615 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H50_RS14805GCF_018264005#E1H50_RS14805
HKClassic

3 183 591-3 185 927 nt · Reverse (-)

Old locus E1H50_15190RefSeq WP_022621102.1
E1H50_RS14810GCF_018264005#E1H50_RS14810
RROmpRCurrent focus

3 185 899-3 186 615 nt · Reverse (-)

Old locus E1H50_15195RefSeq WP_003431132.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0932517Run 7 · RR · 2174 sequences
Representative sequenceGCF_000154625#QAB_RS0215280Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_0932517

Simplified PFAM architecture for RROC_0932517

PFAM domain coverage: 183 / 238 aa (76.9%)

1 aa238 aa
Response_reg: 6-114 aaResponse_regResponse_reg: 6-114 aaResponse_regTrans_reg_C: 161-234 aaTrans_reg_CTrans_reg_C: 161-234 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[6-114] | Trans_reg_C[161-234]
  • Domain count: 2
  • Matched identifier: RROC_0932517
  • Positioned domains: Response_reg 6-114 ; Response_reg 6-114 ; Trans_reg_C 161-234 ; Trans_reg_C 161-234
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0215280

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264005
AssemblyASM1826400v1 · Contighaploid
Genome composition4 265 397 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key