Gene detail

E1H50_RS10420

Response regulator NtrC family

Clostridioides difficile · GCF_018264005

ClassRRTypeNtrCLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264005#E1H50_RS10420Stable P2CS identifier used across views.
GenomeGCF_018264005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0333967Run 7 · 66 sequences · id 100% · cov 80%
External referencesWP_016728592.1 · MIST4 E1H50_RS10420RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regAAA_5HTH_8
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage271 / 440 aa (61.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Response_reg: 3-114 aa (112 aa)1AAA_5: 157-275 aa (119 aa)2HTH_8: 398-437 aa (40 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
3-114 aa · 112 aa · 25.5% of protein
Raw tokenResponse_reg:3:1.22e-25:114:112:111
2 AAA_5#2
157-275 aa · 119 aa · 27.0% of protein
Raw tokenAAA_5:157:0.00000000312:275:128:135
3 HTH_8#3
398-437 aa · 40 aa · 9.1% of protein
Raw tokenHTH_8:398:0.000000000193:437:40:40
  • Raw architecture: Response_reg:3:1.22e-25:114:112:111#AAA_5:157:0.00000000312:275:128:135#HTH_8:398:0.000000000193:437:40:40
  • Domain description: 1 Response_reg,1 AAA_5,1 HTH_8
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018264005::NZ_SMNN01000001.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2226776-2230092Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H50_10660RefSeq proteinWP_016728592.1
Context group IDGCF_018264005::NZ_SMNN01000001.1::G00032
Context members
E1H50_RS10415E1H50_RS10420
Partner locus tags
E1H50_RS10415E1H50_RS10420
Partner old locus tags
E1H50_10655E1H50_10660
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016728592.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H50_RS10420Primary locus identifier stored in the genes table.
Old locus tagE1H50_10660Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNN01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 228 770-2 230 092 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 226 776-2 230 092 ntGCF_018264005::NZ_SMNN01000001.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018264005::NZ_SMNN01000001.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNN01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 226 776-2 230 092 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 226 776 nt2 230 092 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H50_RS10415GCF_018264005#E1H50_RS10415
HKClassic

2 226 776-2 228 770 nt · Forward (+)

Old locus E1H50_10655RefSeq WP_009896876.1
E1H50_RS10420GCF_018264005#E1H50_RS10420
RRNtrCCurrent focus

2 228 770-2 230 092 nt · Forward (+)

Old locus E1H50_10660RefSeq WP_016728592.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0333967Run 7 · RR · 66 sequences
Representative sequenceGCF_000242355#MUI_RS0102790Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.

PFAM architecture for RROC_0333967

Simplified PFAM architecture for RROC_0333967

PFAM domain coverage: 386 / 440 aa (87.7%)

1 aa440 aa
Response_reg: 3-113 aaResponse_regResponse_reg: 3-113 aaResponse_regSigma54_activat: 137-300 aaSigma54_activatSigma54_activat: 137-300 aaSigma54_activatAAA_lid_14: 306-375 aaAAA_lid_14AAA_lid_14: 306-375 aaAAA_lid_14HTH_8: 397-437 aaHTH_8HTH_8: 397-437 aaHTH_8
Response_regSigma54_activatAAA_lid_14HTH_8
  • Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
  • Raw architecture: Response_reg[3-113] | Sigma54_activat[137-300] | AAA_lid_14[306-375] | HTH_8[397-437]
  • Domain count: 4
  • Matched identifier: RROC_0333967
  • Positioned domains: Response_reg 3-113 ; Response_reg 3-113 ; Sigma54_activat 137-300 ; Sigma54_activat 137-300 ; AAA_lid_14 306-375 ; AAA_lid_14 306-375 ; HTH_8 397-437 ; HTH_8 397-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0102790

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264005
AssemblyASM1826400v1 · Contighaploid
Genome composition4 265 397 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key