Gene detail

KFK07_RS04100

Histidine kinase, Classic

Clostridioides difficile · GCF_018255775

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018255775#KFK07_RS04100Stable P2CS identifier used across views.
GenomeGCF_018255775Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2882103Run 6 · 11 sequences · id 100% · cov 80%
External referencesWP_009255074.1 · A0A411ZXW5 · MIST4 KFK07_RS04100RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage226 / 305 aa (74.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
HAMP: 4-56 aa (53 aa)1HisKA: 85-150 aa (66 aa)2HATPase_c: 197-303 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
4-56 aa · 53 aa · 17.4% of protein
Raw tokenHAMP:4:0.0000194:56:53:69
2 HisKA#2
85-150 aa · 66 aa · 21.6% of protein
Raw tokenHisKA:85:0.0000000148:150:66:64
3 HATPase_c#3
197-303 aa · 107 aa · 35.1% of protein
Raw tokenHATPase_c:197:5.07e-32:303:107:109
  • Raw architecture: HAMP:4:0.0000194:56:53:69#HisKA:85:0.0000000148:150:66:64#HATPase_c:197:5.07e-32:303:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018255775::NZ_CP073752.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span846274-847889Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKFK07_04100RefSeq proteinWP_009255074.1
Context group IDGCF_018255775::NZ_CP073752.1::G00015
Context members
KFK07_RS04095KFK07_RS04100
Partner locus tags
KFK07_RS04095KFK07_RS04100
Partner old locus tags
KFK07_04095KFK07_04100
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009255074.1Primary protein accession used for annex mappings.
UniProt accessionA0A411ZXW5Primary UniProt accession resolved in the annex database.
UniProt IDA0A411ZXW5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKFK07_RS04100Primary locus identifier stored in the genes table.
Old locus tagKFK07_04100Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP073752.1Sequence record reported by the local genomic context database.
Genomic interval846 972-847 889 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span846 274-847 889 ntGCF_018255775::NZ_CP073752.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018255775::NZ_CP073752.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP073752.1All displayed genes belong to this local TCS context.
Neighborhood span846 274-847 889 nt1 616 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
846 274 nt847 889 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

KFK07_RS04095GCF_018255775#KFK07_RS04095
RROmpR

846 274-846 966 nt · Forward (+)

Old locus KFK07_04095RefSeq WP_009255073.1
KFK07_RS04100GCF_018255775#KFK07_RS04100
HKClassicCurrent focus

846 972-847 889 nt · Forward (+)

Old locus KFK07_04100RefSeq WP_009255074.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2882103Run 6 · HK · 11 sequences
Representative sequenceGCF_000451385#QQ5_RS15245Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2882103

Simplified PFAM architecture for HKOC_2882103

PFAM domain coverage: 171 / 305 aa (56.1%)

1 aa305 aa
HisKA: 85-148 aaHisKAHATPase_c: 197-303 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[85-148] | HATPase_c[197-303]
  • Domain count: 2
  • Matched identifier: HKOC_2882103
  • Positioned domains: HisKA 85-148 ; HATPase_c 197-303
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451385#QQ5_RS15245

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018255775
AssemblyASM1825577v1 · Complete Genomehaploid
Genome composition4 208 592 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key