1 HisKA#1
304-371 aa · 68 aa · 12.7% of protein
Raw token
HisKA:304:0.000000000000135:371:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
JMW46_RS12420
Histidine kinase, Classic
Clostridioides difficile · GCF_016767135
ClassHKTypeClassicLength535 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_016767135#JMW46_RS12420Stable P2CS identifier used across views.
GenomeGCF_016767135Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length535 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage178 / 535 aa (33.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa535 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
416-525 aa · 110 aa · 20.6% of protein
Raw token
HATPase_c:416:6.54e-31:525:110:109- Raw architecture: HisKA:304:0.000000000000135:371:68:64#HATPase_c:416:6.54e-31:525:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_016767135::NZ_CP068553.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2708215-2710517Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJMW46_12420RefSeq proteinWP_003417858.1
Context group ID
GCF_016767135::NZ_CP068553.1::G00034Context members
JMW46_RS12420JMW46_RS12425
Partner locus tags
JMW46_RS12420JMW46_RS12425
Partner old locus tags
JMW46_12420JMW46_12425
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003417858.1Primary protein accession used for annex mappings.
UniProt accessionD5Q0A9Primary UniProt accession resolved in the annex database.
UniProt IDD5Q0A9_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagJMW46_RS12420Primary locus identifier stored in the genes table.
Old locus tagJMW46_12420Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP068553.1Sequence record reported by the local genomic context database.
Genomic interval2 708 215-2 709 822 nt1 608 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 708 215-2 710 517 ntGCF_016767135::NZ_CP068553.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_016767135::NZ_CP068553.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP068553.1All displayed genes belong to this local TCS context.
Neighborhood span2 708 215-2 710 517 nt2 303 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 708 215 nt2 710 517 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
JMW46_RS12420GCF_016767135#JMW46_RS12420
HKClassicCurrent focus
2 708 215-2 709 822 nt · Forward (+)
JMW46_RS12425GCF_016767135#JMW46_RS12425
RROmpR
2 709 813-2 710 517 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164175#HMPREF0220_RS08690Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1338518
Simplified PFAM architecture for HKOC_1338518
PFAM domain coverage: 286 / 535 aa (53.5%)
1 aa535 aa
DUF4118HisKAHATPase_c
- Simplified architecture: DUF4118 + HisKA + HATPase_c
- Raw architecture: DUF4118[32-139] | HisKA[304-371] | HATPase_c[416-525]
- Domain count: 3
- Matched identifier: HKOC_1338518
- Positioned domains: DUF4118 32-139 ; HisKA 304-371 ; HATPase_c 416-525
Cluster members and taxonomy
Representative gene: GCF_000164175#HMPREF0220_RS08690
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_016767135
AssemblyASM1676713v1 · Complete Genomehaploid
Genome composition4 070 623 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key