Gene detail

JMW55_RS14620

Histidine kinase, Classic

Clostridioides difficile · GCF_016767035

ClassHKTypeClassicLength641 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_016767035#JMW55_RS14620Stable P2CS identifier used across views.
GenomeGCF_016767035Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860240Run 6 · 300 sequences · id 100% · cov 80%
External referencesWP_235690218.1 · MIST4 JMW55_RS14620RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length641 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage388 / 641 aa (60.5%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa641 aa
SBP_bac_3: 35-255 aa (221 aa)1HisKA: 423-485 aa (63 aa)2HATPase_c: 534-637 aa (104 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
35-255 aa · 221 aa · 34.5% of protein
Raw tokenSBP_bac_3:35:2.05e-42:255:230:224
2 HisKA#2
423-485 aa · 63 aa · 9.8% of protein
Raw tokenHisKA:423:0.0000000000000455:485:63:64
3 HATPase_c#3
534-637 aa · 104 aa · 16.2% of protein
Raw tokenHATPase_c:534:3.46e-23:637:105:109
  • Raw architecture: SBP_bac_3:35:2.05e-42:255:230:224#HisKA:423:0.0000000000000455:485:63:64#HATPase_c:534:3.46e-23:637:105:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_016767035::NZ_CP068560.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3231523-3234770Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJMW55_14620RefSeq proteinWP_235690218.1
Context group IDGCF_016767035::NZ_CP068560.1::G00044
Context members
JMW55_RS14615JMW55_RS14620
Partner locus tags
JMW55_RS14615JMW55_RS14620
Partner old locus tags
JMW55_14615JMW55_14620
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_235690218.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagJMW55_RS14620Primary locus identifier stored in the genes table.
Old locus tagJMW55_14620Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP068560.1Sequence record reported by the local genomic context database.
Genomic interval3 232 845-3 234 770 nt1 926 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 231 523-3 234 770 ntGCF_016767035::NZ_CP068560.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_016767035::NZ_CP068560.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP068560.1All displayed genes belong to this local TCS context.
Neighborhood span3 231 523-3 234 770 nt3 248 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 231 523 nt3 234 770 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

JMW55_RS14615GCF_016767035#JMW55_RS14615
RRNtrC

3 231 523-3 232 845 nt · Reverse (-)

Old locus JMW55_14615RefSeq WP_003423653.1
JMW55_RS14620GCF_016767035#JMW55_RS14620
HKClassicCurrent focus

3 232 845-3 234 770 nt · Reverse (-)

Old locus JMW55_14620RefSeq WP_235690218.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860240Run 6 · HK · 300 sequences
Representative sequenceGCF_000155065#QAE_RS0208605Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860240

Simplified PFAM architecture for HKOC_0860240

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860240
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0208605

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_016767035
AssemblyASM1676703v1 · Complete Genomehaploid
Genome composition3 951 345 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key