Gene detail

JMW49_RS01110

Histidine kinase, Classic

Clostridioides difficile · GCF_016767015

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_016767015#JMW49_RS01110Stable P2CS identifier used across views.
GenomeGCF_016767015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0387827Run 6 · 270 sequences · id 100% · cov 80%
External referencesWP_003424655.1 · A0AAX3H0K9 · MIST4 JMW49_RS01110RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_8HisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 912 aa (24.3%)Merged over positioned domains only.
Domain description1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
PAS_8: 532-569 aa (38 aa)1HisKA: 655-726 aa (72 aa)2HATPase_c: 774-885 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS_8#1
532-569 aa · 38 aa · 4.2% of protein
Raw tokenPAS_8:532:0.0000785:569:38:65
2 HisKA#2
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.00000000518:726:72:64
3 HATPase_c#3
774-885 aa · 112 aa · 12.3% of protein
Raw tokenHATPase_c:774:1.99e-24:885:112:109
  • Raw architecture: PAS_8:532:0.0000785:569:38:65#HisKA:655:0.00000000518:726:72:64#HATPase_c:774:1.99e-24:885:112:109
  • Domain description: 1 PAS_8,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_016767015::NZ_CP068561.1::G00005
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span244742-247480Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJMW49_01110RefSeq proteinWP_003424655.1
Context group IDGCF_016767015::NZ_CP068561.1::G00005
Context members
JMW49_RS01110
Partner locus tags
JMW49_RS01110
Partner old locus tags
JMW49_01110
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003424655.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX3H0K9Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX3H0K9_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagJMW49_RS01110Primary locus identifier stored in the genes table.
Old locus tagJMW49_01110Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP068561.1Sequence record reported by the local genomic context database.
Genomic interval244 742-247 480 nt2 739 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span244 742-247 480 ntGCF_016767015::NZ_CP068561.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_016767015::NZ_CP068561.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP068561.1All displayed genes belong to this local TCS context.
Neighborhood span244 742-247 480 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
244 742 nt247 480 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

JMW49_RS01110GCF_016767015#JMW49_RS01110
HKClassicCurrent focus

244 742-247 480 nt · Reverse (-)

Old locus JMW49_01110RefSeq WP_003424655.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0387827Run 6 · HK · 270 sequences
Representative sequenceGCF_000164655#HMPREF0219_RS03140Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0387827

Simplified PFAM architecture for HKOC_0387827

PFAM domain coverage: 221 / 912 aa (24.2%)

1 aa912 aa
PAS_8: 532-572 aaHisKA: 656-724 aaHisKAHATPase_c: 774-884 aaHATPase_c
PAS_8HisKAHATPase_c
  • Simplified architecture: PAS_8 + HisKA + HATPase_c
  • Raw architecture: PAS_8[532-572] | HisKA[656-724] | HATPase_c[774-884]
  • Domain count: 3
  • Matched identifier: HKOC_0387827
  • Positioned domains: PAS_8 532-572 ; HisKA 656-724 ; HATPase_c 774-884
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164655#HMPREF0219_RS03140

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 270 total members. Page 1 / 6.

GCF_000164655#HMPREF0219_RS03140 (representative)
HMPREF0219_RS03140 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_000164175#HMPREF0220_RS04405
HMPREF0220_RS04405 · HK · Classic
RefSeq: WP_003419962.1
UniProt: D5Q6E4
GCF_000210435#CDM120_RS07785
CDM120_RS07785 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_000499505#BN164_RS06690
BN164_RS06690 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_000582865#BN165_RS06845
BN165_RS06845 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_001050575#BN163_RS06915
BN163_RS06915 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_001972065#BER35_RS07970
BER35_RS07970 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_001972115#BER34_RS11910
BER34_RS11910 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_002301695#BGU20_RS04035
BGU20_RS04035 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_002302685#BGU93_RS15415
BGU93_RS15415 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_002303305#BGU53_RS09510
BGU53_RS09510 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_002352505#V439_RS04885
V439_RS04885 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_002412385#V438_RS17775
V438_RS17775 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_002946535#C4E42_RS11760
C4E42_RS11760 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_003482165#CDIF29020_RS07675
CDIF29020_RS07675 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_003482365#CDIF29747_RS07430
CDIF29747_RS07430 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_003697245#EBL91_RS07335
EBL91_RS07335 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_004318785#E0Q93_RS07145
E0Q93_RS07145 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_008579085#F6C11_RS01895
F6C11_RS01895 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_009362915#FTB24_RS11515
FTB24_RS11515 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_015351855#ITI91_RS07800
ITI91_RS07800 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_015352255#ITJ05_RS17015
ITJ05_RS17015 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016766955#JMW53_RS15630
JMW53_RS15630 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016766975#JMW50_RS04370
JMW50_RS04370 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016766995#JMW52_RS13015
JMW52_RS13015 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016767015#JMW49_RS01110
JMW49_RS01110 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016767035#JMW55_RS15985
JMW55_RS15985 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016767055#JMW51_RS13345
JMW51_RS13345 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016767095#JMW48_RS07675
JMW48_RS07675 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016767115#JMW47_RS04160
JMW47_RS04160 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_016767135#JMW46_RS16845
JMW46_RS16845 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_017592625#J5O10_RS07265
J5O10_RS07265 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_018603395#KK111_RS07510
KK111_RS07510 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_018884725#E1H40_RS07230
E1H40_RS07230 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_019427665#K1N48_RS10715
K1N48_RS10715 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_019427725#K1N54_RS05910
K1N54_RS05910 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_020297505#LA365_RS11070
LA365_RS11070 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021283625#LWE91_RS13550
LWE91_RS13550 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021283665#LWF03_RS15435
LWF03_RS15435 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021283685#LWE71_RS09615
LWE71_RS09615 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021283745#LWE78_RS15705
LWE78_RS15705 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021283845#LWG76_RS11740
LWG76_RS11740 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021283885#LWE86_RS15985
LWE86_RS15985 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021284015#LWE81_RS15880
LWE81_RS15880 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021284065#LWE83_RS10485
LWE83_RS10485 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021284375#LWE89_RS15695
LWE89_RS15695 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_021284405#LWE99_RS15985
LWE99_RS15985 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_022970035#HAV36_RS12285
HAV36_RS12285 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_022970075#MZP62_RS11355
MZP62_RS11355 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9
GCF_022970095#MZP83_RS05750
MZP83_RS05750 · HK · Classic
RefSeq: WP_003424655.1
UniProt: A0AAX3H0K9

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_016767015
AssemblyASM1676701v1 · Complete Genomehaploid
Genome composition3 955 466 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 49 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key