Gene detail

JMW52_RS15805

Histidine kinase, Classic

Clostridioides difficile · GCF_016766995

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_016766995#JMW52_RS15805Stable P2CS identifier used across views.
GenomeGCF_016766995Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504292Run 6 · 309 sequences · id 100% · cov 80%
External referencesWP_003418746.1 · D5Q1H2 · MIST4 JMW52_RS15805RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 212-279 aa (68 aa)1HisKA: 289-347 aa (59 aa)2HATPase_c: 395-495 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw tokenHAMP:212:0.00000597:279:68:69
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw tokenHisKA:289:5.61e-17:347:59:64
3 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw tokenHATPase_c:395:3.04e-27:495:106:109
  • Raw architecture: HAMP:212:0.00000597:279:68:69#HisKA:289:5.61e-17:347:59:64#HATPase_c:395:3.04e-27:495:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_016766995::NZ_CP068558.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3260895-3263088Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJMW52_15270RefSeq proteinWP_003418746.1
Context group IDGCF_016766995::NZ_CP068558.1::G00039
Context members
JMW52_RS15805JMW52_RS15810
Partner locus tags
JMW52_RS15805JMW52_RS15810
Partner old locus tags
JMW52_15270JMW52_15275
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003418746.1Primary protein accession used for annex mappings.
UniProt accessionD5Q1H2Primary UniProt accession resolved in the annex database.
UniProt IDD5Q1H2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagJMW52_RS15805Primary locus identifier stored in the genes table.
Old locus tagJMW52_15270Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP068558.1Sequence record reported by the local genomic context database.
Genomic interval3 260 895-3 262 382 nt1 488 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 260 895-3 263 088 ntGCF_016766995::NZ_CP068558.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_016766995::NZ_CP068558.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP068558.1All displayed genes belong to this local TCS context.
Neighborhood span3 260 895-3 263 088 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 260 895 nt3 263 088 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

JMW52_RS15805GCF_016766995#JMW52_RS15805
HKClassicCurrent focus

3 260 895-3 262 382 nt · Reverse (-)

Old locus JMW52_15270RefSeq WP_003418746.1
JMW52_RS15810GCF_016766995#JMW52_RS15810
RROmpR

3 262 384-3 263 088 nt · Reverse (-)

Old locus JMW52_15275RefSeq WP_003418745.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504292Run 6 · HK · 309 sequences
Representative sequenceGCF_000155065#QAE_RS0204760Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504292

Simplified PFAM architecture for HKOC_1504292

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504292
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0204760

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 309 total members. Page 1 / 7.

GCF_000155065#QAE_RS0204760 (representative)
QAE_RS0204760 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_000164175#HMPREF0220_RS06705
HMPREF0220_RS06705 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_000164655#HMPREF0219_RS07985
HMPREF0219_RS07985 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_000210435#CDM120_RS05420
CDM120_RS05420 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_000499505#BN164_RS04900
BN164_RS04900 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_000531165#BN166_RS12420
BN166_RS12420 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_000582865#BN165_RS04500
BN165_RS04500 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_001050575#BN163_RS04560
BN163_RS04560 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_001972065#BER35_RS05585
BER35_RS05585 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_001972115#BER34_RS18425
BER34_RS18425 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_002301695#BGU20_RS11975
BGU20_RS11975 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_002302685#BGU93_RS01355
BGU93_RS01355 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_002303305#BGU53_RS11205
BGU53_RS11205 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_002352505#V439_RS06450
V439_RS06450 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_002412385#V438_RS17380
V438_RS17380 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_002946515#C4E25_RS05010
C4E25_RS05010 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_002946535#C4E42_RS14180
C4E42_RS14180 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_002946555#C4E26_RS05010
C4E26_RS05010 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_003482165#CDIF29020_RS05255
CDIF29020_RS05255 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_003482365#CDIF29747_RS05010
CDIF29747_RS05010 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_003697205#EBB60_RS05430
EBB60_RS05430 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_003697225#EBL90_RS05575
EBL90_RS05575 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_003697245#EBL91_RS05000
EBL91_RS05000 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_004318565#E0Q96_RS05755
E0Q96_RS05755 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_004318785#E0Q93_RS06415
E0Q93_RS06415 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_008579085#F6C11_RS12640
F6C11_RS12640 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_009362915#FTB24_RS13930
FTB24_RS13930 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_012952655#HCN89_RS05685
HCN89_RS05685 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_015351855#ITI91_RS05435
ITI91_RS05435 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_015352255#ITJ05_RS05400
ITJ05_RS05400 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_015732535#CDIF101085_RS04895
CDIF101085_RS04895 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016766955#JMW53_RS13280
JMW53_RS13280 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016766975#JMW50_RS01915
JMW50_RS01915 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016766995#JMW52_RS15805
JMW52_RS15805 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016767015#JMW49_RS03465
JMW49_RS03465 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016767035#JMW55_RS00405
JMW55_RS00405 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016767055#JMW51_RS15700
JMW51_RS15700 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016767095#JMW48_RS10035
JMW48_RS10035 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016767115#JMW47_RS06515
JMW47_RS06515 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_016767135#JMW46_RS14485
JMW46_RS14485 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_017592625#J5O10_RS04900
J5O10_RS04900 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_018603395#KK111_RS05160
KK111_RS05160 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_018603455#KK110_RS05155
KK110_RS05155 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_018603475#KK112_RS05145
KK112_RS05145 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_018884725#E1H40_RS04860
E1H40_RS04860 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_019427665#K1N48_RS09960
K1N48_RS09960 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_019427725#K1N54_RS02055
K1N54_RS02055 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_019931025#K8P06_RS15645
K8P06_RS15645 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_020297505#LA365_RS13435
LA365_RS13435 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2
GCF_021283625#LWE91_RS01130
LWE91_RS01130 · HK · Classic
RefSeq: WP_003418746.1
UniProt: D5Q1H2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_016766995
AssemblyASM1676699v1 · Complete Genomehaploid
Genome composition4 077 288 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 86 · HK 41 · RR 45CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key