1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw token
HisKA:309:0.000000000000009:375:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
JMW50_RS08535
Histidine kinase, Classic
Clostridioides difficile · GCF_016766975
ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_016766975#JMW50_RS08535Stable P2CS identifier used across views.
GenomeGCF_016766975Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa530 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw token
HATPase_c:428:0.0000000975:513:90:109- Raw architecture: HisKA:309:0.000000000000009:375:67:64#HATPase_c:428:0.0000000975:513:90:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_016766975::NZ_CP068559.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1882293-1884570Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJMW50_08535RefSeq proteinWP_003423136.1
Context group ID
GCF_016766975::NZ_CP068559.1::G00025Context members
JMW50_RS08530JMW50_RS08535
Partner locus tags
JMW50_RS08530JMW50_RS08535
Partner old locus tags
JMW50_08530JMW50_08535
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003423136.1Primary protein accession used for annex mappings.
UniProt accessionD5Q2Z1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q2Z1_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagJMW50_RS08535Primary locus identifier stored in the genes table.
Old locus tagJMW50_08535Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP068559.1Sequence record reported by the local genomic context database.
Genomic interval1 882 978-1 884 570 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 882 293-1 884 570 ntGCF_016766975::NZ_CP068559.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_016766975::NZ_CP068559.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP068559.1All displayed genes belong to this local TCS context.
Neighborhood span1 882 293-1 884 570 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 882 293 nt1 884 570 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
JMW50_RS08530GCF_016766975#JMW50_RS08530
RROmpR
1 882 293-1 883 009 nt · Forward (+)
JMW50_RS08535GCF_016766975#JMW50_RS08535
HKClassicCurrent focus
1 882 978-1 884 570 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0211330Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1355523
Simplified PFAM architecture for HKOC_1355523
PFAM domain coverage: 194 / 530 aa (36.6%)
1 aa530 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[255-297] | HisKA[309-375] | HATPase_c[427-510]
- Domain count: 3
- Matched identifier: HKOC_1355523
- Positioned domains: HAMP 255-297 ; HisKA 309-375 ; HATPase_c 427-510
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0211330
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_016766975
AssemblyASM1676697v1 · Complete Genomehaploid
Genome composition4 001 197 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key