Gene detail

CDIF27147_RS09670

Histidine kinase, Classic

Clostridioides difficile R20291 · GCF_015732555

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015732555#CDIF27147_RS09670Stable P2CS identifier used across views.
GenomeGCF_015732555Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2881994Run 6 · 31 sequences · id 100% · cov 80%
External referencesWP_012816190.1 · A0ABQ1E3Z7 · MIST4 CDIF27147_RS09670RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 305 aa (72.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
HAMP: 4-56 aa (53 aa)1HisKA: 85-150 aa (66 aa)2HATPase_c: 202-304 aa (103 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
4-56 aa · 53 aa · 17.4% of protein
Raw tokenHAMP:4:0.0000864:56:53:69
2 HisKA#2
85-150 aa · 66 aa · 21.6% of protein
Raw tokenHisKA:85:0.00000012:150:66:64
3 HATPase_c#3
202-304 aa · 103 aa · 33.8% of protein
Raw tokenHATPase_c:202:1.05e-30:304:103:109
  • Raw architecture: HAMP:4:0.0000864:56:53:69#HisKA:85:0.00000012:150:66:64#HATPase_c:202:1.05e-30:304:103:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015732555::NZ_CP029423.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2060540-2062155Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF27147_01975RefSeq proteinWP_012816190.1
Context group IDGCF_015732555::NZ_CP029423.1::G00032
Context members
CDIF27147_RS09665CDIF27147_RS09670
Partner locus tags
CDIF27147_RS09665CDIF27147_RS09670
Partner old locus tags
CDIF27147_01974CDIF27147_01975
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012816190.1Primary protein accession used for annex mappings.
UniProt accessionA0ABQ1E3Z7Primary UniProt accession resolved in the annex database.
UniProt IDA0ABQ1E3Z7_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF27147_RS09670Primary locus identifier stored in the genes table.
Old locus tagCDIF27147_01975Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP029423.1Sequence record reported by the local genomic context database.
Genomic interval2 061 238-2 062 155 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 060 540-2 062 155 ntGCF_015732555::NZ_CP029423.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015732555::NZ_CP029423.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP029423.1All displayed genes belong to this local TCS context.
Neighborhood span2 060 540-2 062 155 nt1 616 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 060 540 nt2 062 155 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF27147_RS09665GCF_015732555#CDIF27147_RS09665
RROmpR

2 060 540-2 061 232 nt · Forward (+)

Old locus CDIF27147_01974RefSeq WP_024738629.1
CDIF27147_RS09670GCF_015732555#CDIF27147_RS09670
HKClassicCurrent focus

2 061 238-2 062 155 nt · Forward (+)

Old locus CDIF27147_01975RefSeq WP_012816190.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2881994Run 6 · HK · 31 sequences
Representative sequenceGCF_000027105#CDR20291_RS09540Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2881994

Simplified PFAM architecture for HKOC_2881994

PFAM domain coverage: 170 / 305 aa (55.7%)

1 aa305 aa
HisKA: 85-148 aaHisKAHATPase_c: 199-304 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[85-148] | HATPase_c[199-304]
  • Domain count: 2
  • Matched identifier: HKOC_2881994
  • Positioned domains: HisKA 85-148 ; HATPase_c 199-304
Cluster members and taxonomy
Visualization

Representative gene: GCF_000027105#CDR20291_RS09540

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 645 463 · GCF_015732555
AssemblyASM1573255v1 · Complete Genomehaploid
Genome composition4 204 902 bp · 29,0% GCClostridioides difficile R20291
Signal transduction countsGenes 108 · HK 51 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key