Gene detail

CDIF101085_RS08610

Histidine kinase, Classic

Clostridioides difficile · GCF_015732535

ClassHKTypeClassicLength664 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015732535#CDIF101085_RS08610Stable P2CS identifier used across views.
GenomeGCF_015732535Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860240Run 6 · 300 sequences · id 100% · cov 80%
External referencesWP_003423651.1 · D5Q521 · MIST4 CDIF101085_RS08610RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length664 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage388 / 664 aa (58.4%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa664 aa
SBP_bac_3: 58-278 aa (221 aa)1HisKA: 446-508 aa (63 aa)2HATPase_c: 557-660 aa (104 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
58-278 aa · 221 aa · 33.3% of protein
Raw tokenSBP_bac_3:58:2.94e-42:278:230:224
2 HisKA#2
446-508 aa · 63 aa · 9.5% of protein
Raw tokenHisKA:446:0.0000000000000525:508:63:64
3 HATPase_c#3
557-660 aa · 104 aa · 15.7% of protein
Raw tokenHATPase_c:557:4.84e-23:660:105:109
  • Raw architecture: SBP_bac_3:58:2.94e-42:278:230:224#HisKA:446:0.0000000000000525:508:63:64#HATPase_c:557:4.84e-23:660:105:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015732535::NZ_CP021319.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1815414-1818730Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF101085_01771RefSeq proteinWP_003423651.1
Context group IDGCF_015732535::NZ_CP021319.1::G00026
Context members
CDIF101085_RS08610CDIF101085_RS08615
Partner locus tags
CDIF101085_RS08610CDIF101085_RS08615
Partner old locus tags
CDIF101085_01771CDIF101085_01772
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003423651.1Primary protein accession used for annex mappings.
UniProt accessionD5Q521Primary UniProt accession resolved in the annex database.
UniProt IDD5Q521_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF101085_RS08610Primary locus identifier stored in the genes table.
Old locus tagCDIF101085_01771Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP021319.1Sequence record reported by the local genomic context database.
Genomic interval1 815 414-1 817 408 nt1 995 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 815 414-1 818 730 ntGCF_015732535::NZ_CP021319.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015732535::NZ_CP021319.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP021319.1All displayed genes belong to this local TCS context.
Neighborhood span1 815 414-1 818 730 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 815 414 nt1 818 730 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF101085_RS08610GCF_015732535#CDIF101085_RS08610
HKClassicCurrent focus

1 815 414-1 817 408 nt · Forward (+)

Old locus CDIF101085_01771RefSeq WP_003423651.1
CDIF101085_RS08615GCF_015732535#CDIF101085_RS08615
RRNtrC

1 817 408-1 818 730 nt · Forward (+)

Old locus CDIF101085_01772RefSeq WP_003423653.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860240Run 6 · HK · 300 sequences
Representative sequenceGCF_000155065#QAE_RS0208605Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860240

Simplified PFAM architecture for HKOC_0860240

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860240
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0208605

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_015732535
AssemblyASM1573253v1 · Complete Genomehaploid
Genome composition4 045 635 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key