Gene detail

CDIF101085_RS02645

Histidine kinase, Classic

Clostridioides difficile · GCF_015732535

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015732535#CDIF101085_RS02645Stable P2CS identifier used across views.
GenomeGCF_015732535Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503303Run 6 · 305 sequences · id 100% · cov 80%
External referencesWP_003417468.1 · D5PZZ6 · MIST4 CDIF101085_RS02645RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for CDIF101085_RS02645
Domain-by-domain annotation2 items
1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw tokenHisKA:182:0.0000000000000118:240:59:64
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw tokenHATPase_c:293:9.9e-19:391:100:109
  • Raw architecture: HisKA:182:0.0000000000000118:240:59:64#HATPase_c:293:9.9e-19:391:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015732535::NZ_CP021319.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span498931-500774Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF101085_00538RefSeq proteinWP_003417468.1
Context group IDGCF_015732535::NZ_CP021319.1::G00003
Context members
CDIF101085_RS02645CDIF101085_RS02650
Partner locus tags
CDIF101085_RS02645CDIF101085_RS02650
Partner old locus tags
CDIF101085_00538CDIF101085_00539
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003417468.1Primary protein accession used for annex mappings.
UniProt accessionD5PZZ6Primary UniProt accession resolved in the annex database.
UniProt IDD5PZZ6_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF101085_RS02645Primary locus identifier stored in the genes table.
Old locus tagCDIF101085_00538Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP021319.1Sequence record reported by the local genomic context database.
Genomic interval498 931-500 112 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span498 931-500 774 ntGCF_015732535::NZ_CP021319.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015732535::NZ_CP021319.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP021319.1All displayed genes belong to this local TCS context.
Neighborhood span498 931-500 774 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
498 931 nt500 774 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF101085_RS02650GCF_015732535#CDIF101085_RS02650
RROmpR

500 112-500 774 nt · Reverse (-)

Old locus CDIF101085_00539RefSeq WP_003417470.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503303Run 6 · HK · 305 sequences
Representative sequenceGCF_000155065#QAE_RS0202145Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503303

Simplified PFAM architecture for HKOC_2503303

PFAM domain coverage: 162 / 393 aa (41.2%)

1 aa393 aa
HisKA: 179-240 aaHisKAHATPase_c: 292-391 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[179-240] | HATPase_c[292-391]
  • Domain count: 2
  • Matched identifier: HKOC_2503303
  • Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0202145

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 305 total members. Page 1 / 7.

GCF_000155065#QAE_RS0202145 (representative)
QAE_RS0202145 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_000164175#HMPREF0220_RS09200
HMPREF0220_RS09200 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_000164655#HMPREF0219_RS16455
HMPREF0219_RS16455 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_000210435#CDM120_RS02995
CDM120_RS02995 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_000499505#BN164_RS01960
BN164_RS01960 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_000531165#BN166_RS14495
BN166_RS14495 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_000582865#BN165_RS02190
BN165_RS02190 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_001050575#BN163_RS02235
BN163_RS02235 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_001972065#BER35_RS03150
BER35_RS03150 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_001972115#BER34_RS15990
BER34_RS15990 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002301695#BGU20_RS05235
BGU20_RS05235 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002302685#BGU93_RS15530
BGU93_RS15530 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002303305#BGU53_RS03560
BGU53_RS03560 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002303425#BGU60_RS01850
BGU60_RS01850 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002352505#V439_RS14140
V439_RS14140 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002412385#V438_RS15395
V438_RS15395 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002946515#C4E25_RS02535
C4E25_RS02535 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002946535#C4E42_RS16650
C4E42_RS16650 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_002946555#C4E26_RS02535
C4E26_RS02535 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_003482165#CDIF29020_RS02535
CDIF29020_RS02535 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_003482365#CDIF29747_RS02535
CDIF29747_RS02535 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_003697205#EBB60_RS02975
EBB60_RS02975 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_003697225#EBL90_RS03120
EBL90_RS03120 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_003697245#EBL91_RS02525
EBL91_RS02525 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_004318565#E0Q96_RS02340
E0Q96_RS02340 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_004318785#E0Q93_RS10825
E0Q93_RS10825 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_008579085#F6C11_RS03230
F6C11_RS03230 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_009362915#FTB24_RS16635
FTB24_RS16635 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_012952655#HCN89_RS19825
HCN89_RS19825 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_015351855#ITI91_RS03040
ITI91_RS03040 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_015352255#ITJ05_RS18400
ITJ05_RS18400 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_015732535#CDIF101085_RS02645
CDIF101085_RS02645 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016766955#JMW53_RS10880
JMW53_RS10880 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016766975#JMW50_RS17655
JMW50_RS17655 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016766995#JMW52_RS18050
JMW52_RS18050 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016767015#JMW49_RS05850
JMW49_RS05850 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016767035#JMW55_RS02800
JMW55_RS02800 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016767055#JMW51_RS00040
JMW51_RS00040 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016767095#JMW48_RS12435
JMW48_RS12435 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016767115#JMW47_RS08895
JMW47_RS08895 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_016767135#JMW46_RS12090
JMW46_RS12090 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_017592625#J5O10_RS02485
J5O10_RS02485 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_018603395#KK111_RS02760
KK111_RS02760 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_018603455#KK110_RS02755
KK110_RS02755 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_018603475#KK112_RS02755
KK112_RS02755 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_018884725#E1H40_RS02470
E1H40_RS02470 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_019427665#K1N48_RS19350
K1N48_RS19350 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_019427725#K1N54_RS23410
K1N54_RS23410 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_019931025#K8P06_RS13385
K8P06_RS13385 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6
GCF_020297505#LA365_RS15825
LA365_RS15825 · HK · Classic
RefSeq: WP_003417468.1
UniProt: D5PZZ6

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_015732535
AssemblyASM1573253v1 · Complete Genomehaploid
Genome composition4 045 635 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key