1 HAMP#1
4-56 aa · 53 aa · 17.4% of protein
Raw token
HAMP:4:0.0000168:56:53:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIF101085_RS01615
Histidine kinase, Classic
Clostridioides difficile · GCF_015732535
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015732535#CDIF101085_RS01615Stable P2CS identifier used across views.
GenomeGCF_015732535Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage226 / 305 aa (74.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation3 items
2 HisKA#2
85-150 aa · 66 aa · 21.6% of protein
Raw token
HisKA:85:0.0000000743:150:66:643 HATPase_c#3
197-303 aa · 107 aa · 35.1% of protein
Raw token
HATPase_c:197:2.93e-30:303:107:109- Raw architecture: HAMP:4:0.0000168:56:53:69#HisKA:85:0.0000000743:150:66:64#HATPase_c:197:2.93e-30:303:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_015732535::NZ_CP021319.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span268828-270444Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF101085_00332RefSeq proteinWP_022615787.1
Context group ID
GCF_015732535::NZ_CP021319.1::G00002Context members
CDIF101085_RS01615CDIF101085_RS01620
Partner locus tags
CDIF101085_RS01615CDIF101085_RS01620
Partner old locus tags
CDIF101085_00332CDIF101085_00333
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_022615787.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIF101085_RS01615Primary locus identifier stored in the genes table.
Old locus tagCDIF101085_00332Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP021319.1Sequence record reported by the local genomic context database.
Genomic interval268 828-269 745 nt918 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span268 828-270 444 ntGCF_015732535::NZ_CP021319.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_015732535::NZ_CP021319.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP021319.1All displayed genes belong to this local TCS context.
Neighborhood span268 828-270 444 nt1 617 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
268 828 nt270 444 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDIF101085_RS01615GCF_015732535#CDIF101085_RS01615
HKClassicCurrent focus
268 828-269 745 nt · Reverse (-)
CDIF101085_RS01620GCF_015732535#CDIF101085_RS01620
RROmpR
269 752-270 444 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000531165#BN166_RS15390Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2882127
Simplified PFAM architecture for HKOC_2882127
PFAM domain coverage: 169 / 305 aa (55.4%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[85-148] | HATPase_c[199-303]
- Domain count: 2
- Matched identifier: HKOC_2882127
- Positioned domains: HisKA 85-148 ; HATPase_c 199-303
Cluster members and taxonomy
Representative gene: GCF_000531165#BN166_RS15390
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_015732535
AssemblyASM1573253v1 · Complete Genomehaploid
Genome composition4 045 635 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key