Gene detail

I2E60_RS06640

Histidine kinase, Hybrid

Anaerostipes hadrus · GCF_015554695

ClassHKTypeHybridLength718 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_015554695#I2E60_RS06640Stable P2CS identifier used across views.
GenomeGCF_015554695Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_0737188Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_195465673.1 · MIST4 I2E60_RS06640RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length718 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage303 / 718 aa (42.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa718 aa
HisKA: 337-403 aa (67 aa)1HATPase_c: 450-567 aa (118 aa)2Response_reg: 591-708 aa (118 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
337-403 aa · 67 aa · 9.3% of protein
Raw tokenHisKA:337:0.000000000000234:403:67:64
2 HATPase_c#2
450-567 aa · 118 aa · 16.4% of protein
Raw tokenHATPase_c:450:2.01e-25:567:118:109
3 Response_reg#3
591-708 aa · 118 aa · 16.4% of protein
Raw tokenResponse_reg:591:7.09e-30:708:118:111
  • Raw architecture: HisKA:337:0.000000000000234:403:67:64#HATPase_c:450:2.01e-25:567:118:109#Response_reg:591:7.09e-30:708:118:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_015554695::NZ_JADNJB010000013.1::G00003
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span22902-25058Genomic interval covered by the local TCS group.
Context group IDGCF_015554695::NZ_JADNJB010000013.1::G00003
Context members
I2E60_RS06640
Partner locus tags
I2E60_RS06640
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_195465673.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2E60_RS06640Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNJB010000013.1Sequence record reported by the local genomic context database.
Genomic interval22 902-25 058 nt2 157 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span22 902-25 058 ntGCF_015554695::NZ_JADNJB010000013.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015554695::NZ_JADNJB010000013.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNJB010000013.1All displayed genes belong to this local TCS context.
Neighborhood span22 902-25 058 nt2 157 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
22 902 nt25 058 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0737188Run 6 · HK · 1 sequences
Representative sequenceGCF_015554695#I2E60_RS06640The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0737188

Simplified PFAM architecture for HKOC_0737188

PFAM domain coverage: 300 / 718 aa (41.8%)

1 aa718 aa
HisKA: 337-403 aaHisKAHATPase_c: 451-566 aaHATPase_cResponse_reg: 591-707 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[337-403] | HATPase_c[451-566] | Response_reg[591-707]
  • Domain count: 3
  • Matched identifier: HKOC_0737188
  • Positioned domains: HisKA 337-403 ; HATPase_c 451-566 ; Response_reg 591-707
Cluster members and taxonomy
Visualization

Representative gene: GCF_015554695#I2E60_RS06640

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_015554695
AssemblyASM1555469v1 · Scaffoldhaploid
Genome composition3 245 115 bp · 36,5% GCAnaerostipes hadrus
Signal transduction countsGenes 53 · HK 28 · RR 24CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key