Gene detail

I2E60_RS00175

Histidine kinase, Classic

Anaerostipes hadrus · GCF_015554695

ClassHKTypeClassicLength488 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015554695#I2E60_RS00175Stable P2CS identifier used across views.
GenomeGCF_015554695Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_1553157Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_195465437.1 · MIST4 I2E60_RS00175RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length488 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage257 / 488 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa488 aa
HAMP: 191-263 aa (73 aa)1His_kinase: 279-355 aa (77 aa)2HATPase_c: 377-483 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
191-263 aa · 73 aa · 15.0% of protein
Raw tokenHAMP:191:0.00000000213:263:73:69
2 His_kinase#2
279-355 aa · 77 aa · 15.8% of protein
Raw tokenHis_kinase:279:1.16e-35:355:77:80
3 HATPase_c#3
377-483 aa · 107 aa · 21.9% of protein
Raw tokenHATPase_c:377:0.0000000000000605:483:108:109
  • Raw architecture: HAMP:191:0.00000000213:263:73:69#His_kinase:279:1.16e-35:355:77:80#HATPase_c:377:0.0000000000000605:483:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015554695::NZ_JADNJB010000001.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span33433-36518Genomic interval covered by the local TCS group.
Context group IDGCF_015554695::NZ_JADNJB010000001.1::G00008
Context members
I2E60_RS00170I2E60_RS00175
Partner locus tags
I2E60_RS00170I2E60_RS00175
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_195465437.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2E60_RS00175Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNJB010000001.1Sequence record reported by the local genomic context database.
Genomic interval35 052-36 518 nt1 467 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span33 433-36 518 ntGCF_015554695::NZ_JADNJB010000001.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015554695::NZ_JADNJB010000001.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNJB010000001.1All displayed genes belong to this local TCS context.
Neighborhood span33 433-36 518 nt3 086 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
33 433 nt36 518 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I2E60_RS00170GCF_015554695#I2E60_RS00170
RRunclassified

33 433-35 052 nt · Forward (+)

RefSeq WP_195465436.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1553157Run 6 · HK · 4 sequences
Representative sequenceGCF_015554695#I2E60_RS00175The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1553157

Simplified PFAM architecture for HKOC_1553157

PFAM domain coverage: 236 / 488 aa (48.4%)

1 aa488 aa
HAMP: 211-262 aaHAMPHis_kinase: 279-355 aaHis_kinaseHATPase_c: 376-482 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[211-262] | His_kinase[279-355] | HATPase_c[376-482]
  • Domain count: 3
  • Matched identifier: HKOC_1553157
  • Positioned domains: HAMP 211-262 ; His_kinase 279-355 ; HATPase_c 376-482
Cluster members and taxonomy
Visualization

Representative gene: GCF_015554695#I2E60_RS00175

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_015554695
AssemblyASM1555469v1 · Scaffoldhaploid
Genome composition3 245 115 bp · 36,5% GCAnaerostipes hadrus
Signal transduction countsGenes 53 · HK 28 · RR 24CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key