Gene detail

I2E06_RS12705

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_015553185

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015553185#I2E06_RS12705Stable P2CS identifier used across views.
GenomeGCF_015553185Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_2076051Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_195396898.1 · MIST4 I2E06_RS12705RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 440 aa (54.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
HAMP: 138-204 aa (67 aa)1HisKA: 219-288 aa (70 aa)2HATPase_c: 334-435 aa (102 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
138-204 aa · 67 aa · 15.2% of protein
Raw tokenHAMP:138:0.0000000866:204:67:69
2 HisKA#2
219-288 aa · 70 aa · 15.9% of protein
Raw tokenHisKA:219:0.00000000175:288:70:64
3 HATPase_c#3
334-435 aa · 102 aa · 23.2% of protein
Raw tokenHATPase_c:334:2.58e-23:435:103:109
  • Raw architecture: HAMP:138:0.0000000866:204:67:69#HisKA:219:0.00000000175:288:70:64#HATPase_c:334:2.58e-23:435:103:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015553185::NZ_JADNGF010000029.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span162-2146Genomic interval covered by the local TCS group.
Context group IDGCF_015553185::NZ_JADNGF010000029.1::G00027
Context members
I2E06_RS12700I2E06_RS12705
Partner locus tags
I2E06_RS12700I2E06_RS12705
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_195396898.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2E06_RS12705Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNGF010000029.1Sequence record reported by the local genomic context database.
Genomic interval824-2 146 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span162-2 146 ntGCF_015553185::NZ_JADNGF010000029.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015553185::NZ_JADNGF010000029.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNGF010000029.1All displayed genes belong to this local TCS context.
Neighborhood span162-2 146 nt1 985 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
162 nt2 146 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2076051Run 6 · HK · 1 sequences
Representative sequenceGCF_015553185#I2E06_RS12705The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2076051

Simplified PFAM architecture for HKOC_2076051

PFAM domain coverage: 217 / 440 aa (49.3%)

1 aa440 aa
HAMP: 159-204 aaHAMPHisKA: 220-287 aaHisKAHATPase_c: 334-436 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[159-204] | HisKA[220-287] | HATPase_c[334-436]
  • Domain count: 3
  • Matched identifier: HKOC_2076051
  • Positioned domains: HAMP 159-204 ; HisKA 220-287 ; HATPase_c 334-436
Cluster members and taxonomy
Visualization

Representative gene: GCF_015553185#I2E06_RS12705

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_015553185
AssemblyASM1555318v1 · Scaffoldhaploid
Genome composition3 373 099 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 80 · HK 38 · RR 41CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key