Gene detail

I2D84_RS04090

Histidine kinase, Classic

Dorea longicatena · GCF_015552885

ClassHKTypeClassicLength579 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015552885#I2D84_RS04090Stable P2CS identifier used across views.
GenomeGCF_015552885Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_1167120Run 6 · 13 sequences · id 100% · cov 80%
External referencesWP_006427958.1 · A6BKJ8 · MIST4 I2D84_RS04090RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length579 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage363 / 579 aa (62.7%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa579 aa
dCache_1: 159-269 aa (111 aa)1HAMP: 286-355 aa (70 aa)2His_kinase: 370-449 aa (80 aa)3HATPase_c: 469-570 aa (102 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
159-269 aa · 111 aa · 19.2% of protein
Raw tokendCache_1:159:0.00000027:269:115:195
2 HAMP#2
286-355 aa · 70 aa · 12.1% of protein
Raw tokenHAMP:286:0.000000000721:355:70:69
3 His_kinase#3
370-449 aa · 80 aa · 13.8% of protein
Raw tokenHis_kinase:370:3.52e-34:449:80:80
4 HATPase_c#4
469-570 aa · 102 aa · 17.6% of protein
Raw tokenHATPase_c:469:4.4e-18:570:105:109
  • Raw architecture: dCache_1:159:0.00000027:269:115:195#HAMP:286:0.000000000721:355:70:69#His_kinase:370:3.52e-34:449:80:80#HATPase_c:469:4.4e-18:570:105:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015552885::NZ_JADNFQ010000016.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1938-5265Genomic interval covered by the local TCS group.
Context group IDGCF_015552885::NZ_JADNFQ010000016.1::G00010
Context members
I2D84_RS04085I2D84_RS04090
Partner locus tags
I2D84_RS04085I2D84_RS04090
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_006427958.1Primary protein accession used for annex mappings.
UniProt accessionA6BKJ8Primary UniProt accession resolved in the annex database.
UniProt IDA6BKJ8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2D84_RS04090Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNFQ010000016.1Sequence record reported by the local genomic context database.
Genomic interval3 526-5 265 nt1 740 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 938-5 265 ntGCF_015552885::NZ_JADNFQ010000016.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015552885::NZ_JADNFQ010000016.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNFQ010000016.1All displayed genes belong to this local TCS context.
Neighborhood span1 938-5 265 nt3 328 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 938 nt5 265 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I2D84_RS04085GCF_015552885#I2D84_RS04085
RRunclassified

1 938-3 536 nt · Forward (+)

RefSeq WP_022415990.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1167120Run 6 · HK · 13 sequences
Representative sequenceGCF_000154065#DORLON_RS08965Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1167120

Simplified PFAM architecture for HKOC_1167120

PFAM domain coverage: 459 / 579 aa (79.3%)

1 aa579 aa
dCache_1: 43-267 aadCache_1HAMP: 304-355 aaHAMPHis_kinase: 371-449 aaHis_kinaseHATPase_c: 469-571 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[43-267] | HAMP[304-355] | His_kinase[371-449] | HATPase_c[469-571]
  • Domain count: 4
  • Matched identifier: HKOC_1167120
  • Positioned domains: dCache_1 43-267 ; HAMP 304-355 ; His_kinase 371-449 ; HATPase_c 469-571
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154065#DORLON_RS08965

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 88 431 · GCF_015552885
AssemblyASM1555288v1 · Scaffoldhaploid
Genome composition3 192 614 bp · 41,5% GCDorea longicatena
Signal transduction countsGenes 76 · HK 35 · RR 40CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key