Gene detail

ITJ18_RS02375

Histidine kinase, Classic

Clostridioides difficile · GCF_015352355

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015352355#ITJ18_RS02375Stable P2CS identifier used across views.
GenomeGCF_015352355Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1747611Run 6 · 403 sequences · id 100% · cov 80%
External referencesWP_009893223.1 · A0A0H3N2G1 · MIST4 ITJ18_RS02375RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 166-232 aa (67 aa)1HisKA: 245-312 aa (68 aa)2HATPase_c: 359-465 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.00000414:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000127:312:68:64
3 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:359:1.13e-26:465:108:109
  • Raw architecture: HAMP:166:0.00000414:232:69:69#HisKA:245:0.0000000000000127:312:68:64#HATPase_c:359:1.13e-26:465:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015352355::NZ_JADKRA010000006.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span14743-16875Genomic interval covered by the local TCS group.
Identifiers
Old locus tagITJ18_02375RefSeq proteinWP_009893223.1
Context group IDGCF_015352355::NZ_JADKRA010000006.1::G00052
Context members
ITJ18_RS02375ITJ18_RS02380
Partner locus tags
ITJ18_RS02375ITJ18_RS02380
Partner old locus tags
ITJ18_02375ITJ18_02380
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893223.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N2G1Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N2G1_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagITJ18_RS02375Primary locus identifier stored in the genes table.
Old locus tagITJ18_02375Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JADKRA010000006.1Sequence record reported by the local genomic context database.
Genomic interval14 743-16 146 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span14 743-16 875 ntGCF_015352355::NZ_JADKRA010000006.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015352355::NZ_JADKRA010000006.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADKRA010000006.1All displayed genes belong to this local TCS context.
Neighborhood span14 743-16 875 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
14 743 nt16 875 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ITJ18_RS02375GCF_015352355#ITJ18_RS02375
HKClassicCurrent focus

14 743-16 146 nt · Reverse (-)

Old locus ITJ18_02375RefSeq WP_009893223.1
ITJ18_RS02380GCF_015352355#ITJ18_RS02380
RROmpR

16 150-16 875 nt · Reverse (-)

Old locus ITJ18_02380RefSeq WP_009893221.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747611Run 6 · HK · 403 sequences
Representative sequenceGCF_000003215#QAC_RS0208650Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747611

Simplified PFAM architecture for HKOC_1747611

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1747611
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0208650

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_015352355
AssemblyASM1535235v1 · Scaffoldhaploid
Genome composition4 181 959 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 50 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key