Gene detail

ITJ11_RS02220

Histidine kinase, Classic

Clostridioides difficile · GCF_015352285

ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015352285#ITJ11_RS02220Stable P2CS identifier used across views.
GenomeGCF_015352285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1355678Run 6 · 13 sequences · id 100% · cov 80%
External referencesWP_022619817.1 · MIST4 ITJ11_RS02220RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa530 aa
HisKA: 309-375 aa (67 aa)1HATPase_c: 428-513 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw tokenHisKA:309:0.0000000000000147:375:67:64
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw tokenHATPase_c:428:0.0000000438:513:90:109
  • Raw architecture: HisKA:309:0.0000000000000147:375:67:64#HATPase_c:428:0.0000000438:513:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015352285::NZ_JADKQW020000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span454003-456280Genomic interval covered by the local TCS group.
Identifiers
Old locus tagITJ11_002220RefSeq proteinWP_022619817.1
Context group IDGCF_015352285::NZ_JADKQW020000001.1::G00003
Context members
ITJ11_RS02215ITJ11_RS02220
Partner locus tags
ITJ11_RS02215ITJ11_RS02220
Partner old locus tags
ITJ11_002215ITJ11_002220
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022619817.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagITJ11_RS02220Primary locus identifier stored in the genes table.
Old locus tagITJ11_002220Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JADKQW020000001.1Sequence record reported by the local genomic context database.
Genomic interval454 688-456 280 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span454 003-456 280 ntGCF_015352285::NZ_JADKQW020000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015352285::NZ_JADKQW020000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADKQW020000001.1All displayed genes belong to this local TCS context.
Neighborhood span454 003-456 280 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
454 003 nt456 280 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ITJ11_RS02215GCF_015352285#ITJ11_RS02215
RROmpR

454 003-454 719 nt · Forward (+)

Old locus ITJ11_002215RefSeq WP_021408495.1
ITJ11_RS02220GCF_015352285#ITJ11_RS02220
HKClassicCurrent focus

454 688-456 280 nt · Forward (+)

Old locus ITJ11_002220RefSeq WP_022619817.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1355678Run 6 · HK · 13 sequences
Representative sequenceGCF_000450785#QO7_RS11935Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1355678

Simplified PFAM architecture for HKOC_1355678

PFAM domain coverage: 191 / 530 aa (36.0%)

1 aa530 aa
HAMP: 255-295 aaHAMPHisKA: 310-375 aaHisKAHATPase_c: 427-510 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
  • Domain count: 3
  • Matched identifier: HKOC_1355678
  • Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450785#QO7_RS11935

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_015352285
AssemblyASM1535228v3 · Scaffoldhaploid
Genome composition4 112 687 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 91 · HK 43 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key